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cytochrome P450 family 27 subfamily B member 1

Summary

Gene Symbol

CYP27B1

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 481133
KEGG Gene ID: cfa:481133
PubChem: 481133

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
C21-steroid hormone biosynthetic process	IEA	30032202
glucocorticoid biosynthetic process	IEA	30032202
cholesterol metabolic process	IEA	30032202
cortisol metabolic process	IEA	30032202
cellular response to peptide hormone stimulus	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process

cellular biosynthetic process [inference]

C21-steroid hormone biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process

hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

cortisol metabolic process

cellular biosynthetic process [inference]

C21-steroid hormone biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process

glucocorticoid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

cortisol metabolic process

tertiary alcohol metabolic process [inference]

cortisol metabolic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process

cellular ketone metabolic process [inference]

cortisol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process

glucocorticoid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

cellular ketone metabolic process [inference]

cortisol metabolic process

olefinic compound metabolic process [inference]

cortisol metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process

glucocorticoid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

cortisol metabolic process

tertiary alcohol metabolic process [inference]

cortisol metabolic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

cellular process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

cortisol metabolic process

cellular biosynthetic process [inference]

C21-steroid hormone biosynthetic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to peptide [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to peptide [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process

hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrial inner membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
monooxygenase activity	IEA	22301074
iron ion binding	IEA	22301074
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA	22301074
heme binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cytochrome P450

Functional Category

I: Lipid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 11 in total

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Gene Ontology
C21-steroid hormone biosynthetic process
cellular response to peptide hormone stimulus
cholesterol metabolic process
cortisol metabolic process
glucocorticoid biosynthetic process
heme binding
iron ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

Displaying **all 4** entries
InterPro
Cytochrome P450 superfamily
Cytochrome P450, E-class, group I
Cytochrome P450, conserved site
Cytochrome P450

KEGG BRITE Database

Orthology

K07438

Name

calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase) [EC:1.14.15.18]

References

Ortholog

Displaying entries **1 - 10** of 76 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	1594	HUMAN13865
Mus musculus	13115	MOUSE00710
Rattus norvegicus	114700	RATNO37965
Sus scrofa	397055	PIGXX25705
Pan troglodytes	452027	PANTR05438
Bos taurus	539630	BOVIN29534
Macaca mulatta	715747	MACMU04637
Danio rerio	793309	DANRE02378
Monodelphis domestica	100031497	MONDO00467
Oryctolagus cuniculus	100341053	RABIT14528