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triokinase and FMN cyclase

Summary

Gene Symbol

TKFC

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 483800
KEGG Gene ID: cfa:483800
PubChem: 483800

Annotation

Keyword

ATP-binding
Cobalt
FAD
Kinase
Multifunctional enzyme
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8C0Q8D4	Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)
F1Q0K5	Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
glycerol catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol catabolic process

alditol catabolic process [inference]

glycerol catabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol catabolic process

alditol catabolic process [inference]

glycerol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol catabolic process

alditol catabolic process [inference]

glycerol catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol catabolic process

alditol catabolic process [inference]

glycerol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

glycerol catabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glycerone kinase activity	IEA	22301074 30032202
ATP binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

glycerone kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

glycerone kinase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dihydroxyacetone kinase

Functional Category

G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
K: Transcription

Displaying **all 8** entries
Gene Ontology
ATP binding
glycerol catabolic process
glycerol metabolic process
glycerone kinase activity
kinase activity
nucleotide binding
phosphorylation
transferase activity

Displaying **all 4** entries
InterPro
DhaK domain
DhaL domain superfamily
DhaL domain
Dihydroxyacetone kinase

KEGG BRITE Database

Orthology

K00863

Name

triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]

References

Rhea

RHEA:13729

FAD

H⁺ + AMP + riboflavin cyclic-4',5'-phosphate

Enzyme

4.6.1.15

PMID

RHEA:13941

D-glyceraldehyde + ATP

H⁺ + ADP + D-glyceraldehyde 3-phosphate

Enzyme

2.7.1.28

PMID

RHEA:15773

dihydroxyacetone + ATP

H⁺ + ADP + dihydroxyacetone phosphate

Enzyme

2.7.1.29

PMID

Ortholog

Displaying entries **1 - 10** of **110** in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	26007	HUMAN06387
Mus musculus	225913	MOUSE26094
Rattus norvegicus	361730	RATNO19145
Pan troglodytes	466626	PANTR03071
Bos taurus	512373	BOVIN23223
Macaca mulatta	694117	MACMU09427
Danio rerio	793926	DANRE41267
Monodelphis domestica	100029804	MONDO26817
Equus caballus	100059639	HORSE06031
Ornithorhynchus anatinus	100076247	ORNAN17660

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Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements