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Guidelines
MIRAGE
tripeptidyl peptidase 1

Summary
Gene Symbol
  • TPP1
Organism
Canis lupus familiaris (dog)
NCBI Gene
485337
PubChem
485337
Annotation
Keyword
  • Autocatalytic cleavage
  • Calcium
  • Disulfide bond
  • Glycoprotein
  • Lysosome
  • Metal-binding
  • Reference proteome
  • Serine protease
  • Signal
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
Q9XSB8
  • Lysosomal pepstatin-insensitive protease
  • Tripeptidyl aminopeptidase
  • Tripeptidyl-peptidase I
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 5 entries
GO Term Evidence Code PMID
proteolysis
nervous system development
central nervous system development
peptide catabolic process
bone resorption
GO Hierarchy
Displaying entries 1 - 5 of 8 in total
GO Term Evidence Code PMID
endopeptidase activity
serine-type endopeptidase activity
peptidase activity
serine-type peptidase activity
tripeptidyl-peptidase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Tripeptidyl peptidase a
Functional Category
  • M: Cell wall/membrane/envelope biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • P: Inorganic ion transport and metabolism
Displaying all 6 entries
Gene Ontology
hydrolase activity
metal ion binding
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity
tripeptidyl-peptidase activity
Displaying all 4 entries
InterPro
Peptidase S53, activation domain
Peptidase S8/S53 domain superfamily
Peptidase S8/S53 domain
Sedolisin domain
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025