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Repository for lectin-assisted multimodality data
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Standards Ontologies Notations
Guidelines
MIRAGE
MBL associated serine protease 1

Summary
Gene Symbol
  • MASP1
Organism
Canis lupus familiaris (dog)
NCBI Gene
488121
KEGG Gene ID
cfa:488121
PubChem
488121
Annotation
Keyword
  • Autocatalytic cleavage
  • Calcium
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Hydroxylation
  • Innate immunity
  • Metal-binding
  • Reference proteome
  • Repeat
  • Serine protease
  • Signal
  • Sushi
Proteins
Displaying all 5 entries
UniProt Protein Name
A0A8I3PJ55
A0A8I3PF98
A0A8C0P4N4
A0A8C0NS70
A0A8C0NV46
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
complement activation
zymogen activation
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
mannan-binding lectin serine
Functional Category
  • G: Carbohydrate transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 9 entries
Gene Ontology
calcium ion binding
complement activation, classical pathway
complement activation
hydrolase activity
immune system process
metal ion binding
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity
Displaying entries 1 - 10 of 13 in total
InterPro
CUB domain
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
Peptidase S1, PA clan, chymotrypsin-like fold
Peptidase S1, PA clan
Peptidase S1A, chymotrypsin family
Peptidase S1A, complement C1r/C1S/mannan-binding
Serine proteases, trypsin domain
Serine proteases, trypsin family, serine active site
Ortholog
Displaying entries 1 - 10 of 76 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
5648 HUMAN73965
17174 MOUSE19135
64023 RATNO03703
460925 PANTR32894
522347 BOVIN14807
708206 MACMU29120
100009493 RABIT04670
100012016 MONDO31913
100068261 HORSE14129
100082252 ORNAN25025
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025