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ATP binding cassette subfamily B member 11

Summary

Gene Symbol

ABCB11

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 488390
PubChem: 488390

Annotation

Keyword

ATP-binding
Cell membrane
Endosome
Glycoprotein
Phosphoprotein
Reference proteome
Repeat
Translocase
Transmembrane helix
Transport
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
B8K1W2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 14 in total

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GO Term	Evidence Code	PMID
xenobiotic metabolic process
phospholipid homeostasis
regulation of fatty acid beta-oxidation
bile acid metabolic process
positive regulation of bile acid secretion

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

xenobiotic metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

bile acid metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

bile acid metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

bile acid metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic hydroxy compound metabolic process [inference]

bile acid metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

xenobiotic metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

transmembrane transport

export from cell [inference]

xenobiotic export from cell

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

phospholipid homeostasis

sterol homeostasis [inference]

cholesterol homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

xenobiotic transport [inference]

secretion [inference]

canalicular bile acid transport

transmembrane transport

organic substance transport [inference]

lipid transport [inference]

bile acid and bile salt transport

canalicular bile acid transport

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

canalicular bile acid transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

canalicular bile acid transport

organic hydroxy compound transport [inference]

bile acid and bile salt transport

canalicular bile acid transport

export from cell [inference]

xenobiotic export from cell

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of fatty acid beta-oxidation

regulation of lipid catabolic process [inference]

regulation of fatty acid beta-oxidation

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid oxidation [inference]

regulation of fatty acid beta-oxidation

regulation of cellular catabolic process [inference]

regulation of fatty acid beta-oxidation

regulation of bile acid metabolic process

regulation of small molecule metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid oxidation [inference]

regulation of fatty acid beta-oxidation

regulation of bile acid metabolic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid oxidation [inference]

regulation of fatty acid beta-oxidation

regulation of steroid metabolic process [inference]

regulation of bile acid metabolic process

regulation of lipid catabolic process [inference]

regulation of fatty acid beta-oxidation

regulation of localization [inference]

regulation of transport [inference]

regulation of organic acid transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of bile acid secretion

regulation of bile acid secretion [inference]

positive regulation of bile acid secretion

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of bile acid secretion

regulation of bile acid secretion [inference]

positive regulation of bile acid secretion

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of bile acid secretion

positive regulation of secretion [inference]

positive regulation of bile acid secretion

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of bile acid secretion

positive regulation of secretion [inference]

positive regulation of bile acid secretion

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid oxidation [inference]

regulation of fatty acid beta-oxidation

regulation of cellular catabolic process [inference]

regulation of fatty acid beta-oxidation

regulation of bile acid metabolic process

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
endosome
cell surface
intracellular canaliculus
recycling endosome membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

recycling endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

recycling endosome membrane

plasma membrane region [inference]

apical plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

intercellular canaliculus

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

recycling endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

recycling endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

recycling endosome

intracellular canaliculus

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
ABC-type transporter activity	IEA	22301074
ABC-type bile acid transporter activity
canalicular bile acid transmembrane transporter activity
ATP hydrolysis activity	IEA	22301074
ABC-type xenobiotic transporter activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

lipid transporter activity [inference]

bile acid transmembrane transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ABC-type transporter activity

xenobiotic transmembrane transporter activity [inference]

ABC-type xenobiotic transporter activity

organic hydroxy compound transmembrane transporter activity [inference]

bile acid transmembrane transporter activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ABC-type transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ABC

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **51 - 60** of **127** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Carlito syrichta	103275445		CARSF12831
Poecilia reticulata	103474346		POERE21614
Ursus maritimus	103659533	29073_0:000596
Nannospalax galili	103737989		NANGA18573
Serinus canaria	103814412		SERCA06852
Rhinopithecus roxellana	104655035		RHIRO14438
Esox lucius	105019995		ESOLU64806
Macaca nemestrina	105483284		MACNE19084
Mandrillus leucophaeus	105545300		MANLE21165
Cercocebus atys	105579758		CERAT00009

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OrthoDB (Group)

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Acknowledgements