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MIRAGE
solute carrier family 11 member 2
Summary
- Gene Symbol
-
- SLC11A2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Endosome
- Glycoprotein
- Golgi apparatus
- Iron transport
- Lysosome
- Mitochondrion outer membrane
- Phosphoprotein
- Reference proteome
- Symport
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P49281 |
|
| A0A0X8GKR4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia | ||
| detection of oxygen | ||
| heme biosynthetic process | ||
| cobalt ion transport | ||
| cobalt ion transport |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
homeostatic process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| lysosome | ||
| lysosomal membrane | ||
| lysosomal membrane | ||
| lysosomal membrane | ||
| early endosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| copper ion transmembrane transporter activity | ||
| iron ion transmembrane transporter activity | ||
| manganese ion transmembrane transporter activity | ||
| manganese ion transmembrane transporter activity | ||
| zinc ion transmembrane transporter activity |
GO Hierarchy
- calcium ion transmembrane transporter activity
- copper ion transmembrane transporter activity
- manganese ion transmembrane transporter activity
- zinc ion transmembrane transporter activity
- cadmium ion transmembrane transporter activity
- cobalt ion transmembrane transporter activity
- nickel cation transmembrane transporter activity
- vanadium ion transmembrane transporter activity
- lead ion transmembrane transporter activity
- calcium ion transmembrane transporter activity
- copper ion transmembrane transporter activity
- manganese ion transmembrane transporter activity
- zinc ion transmembrane transporter activity
- cadmium ion transmembrane transporter activity
- cobalt ion transmembrane transporter activity
- nickel cation transmembrane transporter activity
- vanadium ion transmembrane transporter activity
- chromium ion transmembrane transporter activity
molecular function
transporter activity [inference]
transmembrane transporter activity [inference]
monoatomic ion transmembrane transporter activity [inference]
monoatomic cation transmembrane transporter activity [inference]
metal ion transmembrane transporter activity [inference]
transition metal ion transmembrane transporter activity
inorganic molecular entity transmembrane transporter activity [inference]
inorganic cation transmembrane transporter activity
metal ion transmembrane transporter activity [inference]
transition metal ion transmembrane transporter activity
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- transporter
- Functional Category
-
- K: Transcription
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cadmium ion transmembrane transporter activity |
| manganese ion transmembrane transporter activity |
| metal ion transmembrane transporter activity |
| InterPro |
|---|
| NRAMP family |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11759 | hypochromic anemia | |
| DOID:14330 | Parkinson's disease | |
| DOID:2355 | anemia | |
| DOID:332 | amyotrophic lateral sclerosis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 122224548 | PANLE16464 |
