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5'-nucleotidase ecto
Summary
- Gene Symbol
-
- NT5E
- Aliases
-
- CALJA
- CD73
- eN
- eNT
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- GPI-anchor
- Hydrolase
- Metal-binding
- Nucleotide-binding
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to ATP | ||
| leukocyte cell-cell adhesion | ||
| ADP catabolic process | ||
| AMP catabolic process | ||
| ATP metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
catabolic process [inference]
cellular catabolic process [inference]
organic substance catabolic process [inference]
biosynthetic process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
cellular biosynthetic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
heterocycle catabolic process [inference]
primary metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
organophosphate metabolic process [inference]
carbohydrate derivative metabolic process [inference]
organic cyclic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
organic cyclic compound catabolic process [inference]
organonitrogen compound metabolic process [inference]
organic substance catabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
cellular biosynthetic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
heterocycle catabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular exosome | ||
| nucleoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| XMP 5'-nucleosidase activity | ||
| thymidylate 5'-phosphatase activity | ||
| zinc ion binding | ||
| IMP 5'-nucleotidase activity | ||
| protein binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090072 | hypogonadotropic hypogonadism 12 with or without anosmia | |
| DOID:0090073 | hypogonadotropic hypogonadism 13 with or without anosmia | |
| DOID:0090074 | hypogonadotropic hypogonadism 8 with or without anosmia | |
| DOID:0090076 | hypogonadotropic hypogonadism 18 with or without anosmia | |
| DOID:0090077 | hypogonadotropic hypogonadism 4 with or without anosmia | |
| DOID:0090078 | hypogonadotropic hypogonadism 7 with or without anosmia | |
| DOID:0090079 | hypogonadotropic hypogonadism 17 with or without anosmia | |
| DOID:0090080 | hypogonadotropic hypogonadism 16 with or without anosmia | |
| DOID:0090081 | hypogonadotropic hypogonadism 22 with or without anosmia | |
| DOID:0090082 | hypogonadotropic hypogonadism 20 with or without anosmia |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0001717 | Coronary artery calcification |
| HP:0003207 | Arterial calcification |
| HP:0004417 | Intermittent claudication |
| HP:0005116 | Arterial tortuosity |
| HP:0005645 | Intervertebral disk calcification |
| HP:0011025 | Abnormal cardiovascular system physiology |
| HP:0011986 | Ectopic ossification |
| HP:0012101 | Decreased serum creatinine |
| Disease ID | Disease Name |
|---|---|
| ORPHA:289601 |
|
| OMIM:211800 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 111574556 | AMPOC08609 | ||
| 116839373 | CHEAB16717 | ||
| 115037340 | ECHNA31131 | ||
| 115402090 | SALFA04412 | ||
| 103381340 | CYNSE27076 | ||
| 105805337 | PROCO12958 | ||
| 109100426 | CYPCA104362 | ||
| 122141088 | CYPCA81587 | ||
| 103732145 | NANGA22614 | ||
| 116442221 | CORMO19224 |
