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erythropoietin

Summary

Gene Symbol

EPO

Organism

Felis catus (domestic cat)

External Links

NCBI Gene: 493801
PubChem: 493801

Annotation

Keyword

Disulfide bond
Erythrocyte maturation
Glycoprotein
Hormone
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P33708

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
positive regulation of cell population proliferation
erythrocyte differentiation
erythropoietin-mediated signaling pathway
erythrocyte maturation
positive regulation of Ras protein signal transduction

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

erythropoietin-mediated signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

cell maturation [inference]

erythrocyte maturation

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

erythrocyte maturation

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

cell maturation [inference]

erythrocyte maturation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

erythropoietin-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA	22301074 30032202
extracellular space	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytokine activity	IEA	30032202
erythropoietin receptor binding	IEA	22301074 30032202
hormone activity	IEA	22301074
protein kinase activator activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

erythropoietin receptor binding

receptor ligand activity [inference]

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Erythropoietin

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
cytokine activity
erythrocyte maturation
erythropoietin receptor binding
erythropoietin-mediated signaling pathway
hormone activity
nucleate erythrocyte development
positive regulation of Ras protein signal transduction
positive regulation of cell population proliferation
protein kinase activator activity

Displaying **all 3** entries
InterPro
Erythropoietin/thrombopoietin
Erythropoietin
Four-helical cytokine-like, core

Ortholog

Displaying entries **11 - 20** of 64 in total

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Species	Gene ID	Orthologous MAtrix
Oryctolagus cuniculus	100008786	RABIT11321
Equus caballus	100033849	HORSE06627
Callithrix jacchus	100394313	CALJA25853
Pongo abelii	100459890	PONAB33766
Ailuropoda melanoleuca	100483785	AILME04474
Nomascus leucogenys	100607433	NOMLE12557
Oreochromis niloticus	100707671	ORENI49383
Cavia porcellus	100712648	CAVPO13468
Cricetulus griseus	100753960	CRIGR20872
Sarcophilus harrisii	100924490	SARHA15256