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Standards Ontologies Notations
cytochrome P450, family 17, subfamily A, polypeptide 1

Summary
Gene Symbol
  • CYP17A1
Organism
Ovis aries (sheep)
External Links
NCBI Gene
493968
KEGG Gene ID
oas:493968
PubChem
493968
Annotation
Keyword
  • Heme
  • Lipid metabolism
  • Lyase
  • Membrane
  • Microsome
  • Monooxygenase
  • Reference proteome
  • Steroidogenesis
Proteins
Displaying 1 entry
UniProt Protein Name
Q29497
  • 17-alpha-hydroxyprogesterone aldolase
  • CYPXVII
  • Cytochrome P450 17A1
  • Cytochrome P450-C17
  • Steroid 17-alpha-monooxygenase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
hormone biosynthetic process
progesterone metabolic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
KEGG BRITE Database
Orthology
K00512
Name
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
References
Rhea

RHEA:14753

O2 + 17α-hydroxyprogesterone
H2O + H+ + androst-4-ene-3,17-dione + acetate
Enzyme
PMID

RHEA:50244

O2 + 17α-hydroxypregnenolone
H2O + H+ + 3β-hydroxyandrost-5-en-17-one + acetate
Enzyme
PMID

RHEA:46308

O2 + progesterone
H2O + H+ + 17α-hydroxyprogesterone
Enzyme
PMID

RHEA:65760

O2 + a C21-steroid
a 17α-hydroxy-C21-steroid + H2O + H+
Enzyme
PMID

RHEA:50236

O2 + pregnenolone
H2O + H+ + 17α-hydroxypregnenolone
Enzyme
PMID
Ortholog
Displaying entries 51 - 60 of 87 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
103681600 URSMA04104
114035758 VOMUR03347
113884492 BOBOX21176
113884520 BOBOX21176
113884536 BOBOX21176
105874387 MICMU12732
100959209 OTOGA14208
100125798 TAKRU39290
115249663 TAKRU39290
102011010 CHILA18877
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024