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fucosyltransferase 3

Summary

Gene Symbol

FUT3

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 493975
KEGG Gene ID: ptr:493975
PubChem: 493975

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid metabolism
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O19058	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase Alpha-3-fucosyltransferase FUT3 Alpha-3/4-fucosyltransferase Blood group Lewis alpha-4-fucosyltransferase Fucosyltransferase 3 Fucosyltransferase III

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protein N-linked glycosylation
protein O-linked glycosylation
lipid metabolic process
regulation of cell population proliferation
positive regulation of cell-cell adhesion

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

lipid metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

fucosylation

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

lipid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion

regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion

regulation of cell motility [inference]

regulation of cell migration

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074 30032202
Golgi cisterna membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

Golgi cisterna membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity
alpha-(1->3)-fucosyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity [inference]

3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity

alpha-(1->3)-fucosyltransferase activity

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00716

Name

galactoside 3(4)-fucosyltransferase 3 [EC:2.4.1.65]

References

1977660

Reactions

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KEGG Reaction	Enzyme	Acceptor	Product
R06230	2.4.1.- 2.4.1.152 2.4.1.65	G84034JH	G65223RT
R06227	2.4.1.- 2.4.1.152 2.4.1.65	G07075ZE	G03564IA
R06075	2.4.1.- 2.4.1.65	G01767JJ	G96401FK
R06155	2.4.1.65	G00049MO	G26123AX
R06038	2.4.1.- 2.4.1.152 2.4.1.65	G84034JH	G76439VL
R13173	2.4.1.65	G96538JO	G72748AQ
R06165	2.4.1.65	G79536OW	G50321QR
R06039	2.4.1.- 2.4.1.152 2.4.1.65	G77285LE	G00851XQ
R06162	2.4.1.65	G82858KU	G71485PH
R06025	2.4.1.- 2.4.1.152 2.4.1.65	G58896AZ	G72002FC

Rhea

RHEA:14257

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

a β-D-galactosyl-(1→4)-[α-L-fucosyl-(1→3)]-N-acetyl-β-D-glucosaminyl derivative + H⁺ + GDP

Enzyme

2.4.1.152

PMID

RHEA:23628

a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

a β-D-galactosyl-(1→3)-[α-L-fucosyl-(1→4)]-N-acetyl-β-D-glucosaminyl derivative + H⁺ + GDP

Enzyme

2.4.1.65

PMID

Ortholog

Displaying entries **1 - 10** of 21 in total

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Species	Gene ID	Orthologous MAtrix
Meleagris gallopavo	100544367	MELGA09441
Macaca fascicularis	102145756	MACFA16979
Gorilla gorilla gorilla	129528860	GORGO17116
Pan paniscus	100982431	PANPA19234
Homo sapiens	2525	HUMAN40040
Canis lupus familiaris	449024	CANLF07980
Ailuropoda melanoleuca	100468460	AILME01120
Loxodonta africana	100662623	LOXAF02415
Loxodonta africana	100675894	LOXAF02415
Sus scrofa	100513844	PIGXX18729

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements