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Standards Ontologies Notations
ST6 beta-galactoside alpha-2,6-sialyltransferase 2

Summary
Gene Symbol
  • ST6GAL2
Organism
Bos taurus (domestic cattle)
NCBI Gene
493992
KEGG Gene ID
bta:493992
PubChem
493992
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
A5D7T4
  • CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2
  • ST6Gal II
  • Sialyltransferase 2
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
KEGG BRITE Database
Orthology
K00779
Name
beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.3.1]
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R06188
Rhea

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP
Enzyme
PMID

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP
Enzyme
PMID

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 86 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
84620 HUMAN64203
240119 MOUSE20017
301155 RATNO43159
450198 PANTR28394
481315 CANLF01725
713552 MACMU07601
100019249 MONDO31624
100062033 HORSE10345
100077134 ORNAN15103
100230425 TAEGU10590
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024