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cytochrome P450 family 1 subfamily A member 2

Summary

Gene Symbol

CYP1A2

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 494010
KEGG Gene ID: cfa:494010
PubChem: 494010

Annotation

Keyword

Heme
Lipid metabolism
Lyase
Membrane
Microsome
Monooxygenase
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5R2U2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
hormone biosynthetic process	IEA	30032202
progesterone metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

hormone biosynthetic process

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

hormone biosynthetic process

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

progesterone metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

small molecule metabolic process [inference]

cellular ketone metabolic process [inference]

progesterone metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

cellular ketone metabolic process [inference]

progesterone metabolic process

olefinic compound metabolic process [inference]

progesterone metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

cellular process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

progesterone metabolic process

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

hormone biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
steroid 17-alpha-monooxygenase activity	IEA	30032202
iron ion binding	IEA	22301074
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA	22301074
17-alpha-hydroxyprogesterone aldolase activity	IEA	30032202
heme binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

steroid hydroxylase activity [inference]

steroid 17-alpha-monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

aldehyde-lyase activity [inference]

17-alpha-hydroxyprogesterone aldolase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K07409

Name

cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]

References

3755823

Rhea

an organic molecule + O₂

H₂O + H⁺ + an alcohol

Enzyme

1.14.14.1

PMID

Ortholog

Displaying entries **21 - 30** of 60 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Vulpes vulpes	112917417		VULVU00379
Ursus americanus	123790681		URSAM08951
Ailuropoda melanoleuca	100472774		AILME08969
Felis catus	554345		FELCA14718
Panthera leo	122221159		PANLE19447
Tursiops truncatus	101329596		TURTR15343
Balaenoptera musculus	118891291		BALMU29370
Loxodonta africana	100666189		LOXAF10630
Equus caballus	100062244		HORSE17226
Sus scrofa	100152910		PIGXX32053

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Last updated: August 19, 2024