GlyCosmos Portal

Annotation

Keyword

3D-structure
Cell membrane
Copper
Disulfide bond
GPI-anchor
Golgi apparatus
Metal-binding
Prion
Reference proteome
Repeat
Signal
Transmembrane helix
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P49927
Q5PSB2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein destabilization
positive regulation of neuron apoptotic process
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of calcium-mediated signaling
protein homooligomerization	IEA	22301074

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

response to stimulus [inference]

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to peptide [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to inorganic substance [inference]

response to metal ion [inference]

response to copper ion [inference]

cellular response to copper ion

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to peptide [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to oxygen-containing compound [inference]

response to peptide [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of glutamate receptor signaling pathway [inference]

positive regulation of glutamate receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of glutamate receptor signaling pathway [inference]

positive regulation of glutamate receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of glutamate receptor signaling pathway [inference]

positive regulation of glutamate receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of glutamate receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

regulation of biological quality [inference]

regulation of protein stability [inference]

protein destabilization

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
Golgi apparatus
cytosol
plasma membrane
cell surface
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body

membrane

plasma membrane

organelle membrane [inference]

nuclear membrane

membrane microdomain [inference]

membrane raft

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

side of membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
amyloid-beta binding
copper ion binding
microtubule binding
tubulin binding
identical protein binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

tubulin binding

microtubule binding

identical protein binding

amide binding [inference]

peptide binding [inference]

amyloid-beta binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

cuprous ion binding

protein-containing complex binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

molecular condensate scaffold activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

prion protein

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
metal ion binding
protein homooligomerization

Displaying **all 3** entries
InterPro
Prion protein
Prion/Doppel beta-ribbon domain superfamily
Prion/Doppel protein, beta-ribbon domain

KEGG BRITE Database

Orthology

K05634

Name

prion protein

References

Ortholog

Displaying entries **21 - 30** of 50 in total

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Species	Gene ID	Orthologous MAtrix
Papio anubis	101012637	PAPAN11277
Saimiri boliviensis boliviensis	101039770	SAIBB34358
Felis catus	101087310	FELCA07534
Gorilla gorilla gorilla	101135304	GORGO22424
Tursiops truncatus	101318154	TURTR03883
Ochotona princeps	101521014	OCHPR08480
Octodon degus	101574925	OCTDE12049
Jaculus jaculus	101611209	JACJA13046
Mustela putorius furo	101677643	MUSPF04656
Ictidomys tridecemlineatus	101959784	ICTTR08204

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements