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lymphotoxin alpha

Summary

Gene Symbol

LTA

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 494185
PubChem: 494185

Annotation

Keyword

Cytokine
Glycoprotein
Membrane
Reference proteome
Secreted
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A663DF78	TNF-beta Tumor necrosis factor ligand superfamily member 1
A0A2J8NXP8	TNF-beta Tumor necrosis factor ligand superfamily member 1
P61125	TNF-beta Tumor necrosis factor ligand superfamily member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
immune response	IEA	22301074

GO Hierarchy

biological process

immune system process [inference]

immune response

response to stimulus [inference]

immune response

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074
extracellular space

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
tumor necrosis factor receptor binding	IEA	22301074
cytokine activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

tumor necrosis factor receptor superfamily binding [inference]

tumor necrosis factor receptor binding

receptor ligand activity [inference]

cytokine activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

Tumour necrosis factor

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 10** entries
Gene Ontology
cell communication
cytokine activity
defense response to Gram-positive bacterium
humoral immune response
immune response
lymph node development
positive regulation of chronic inflammatory response to antigenic stimulus
positive regulation of humoral immune response mediated by circulating immunoglobulin
signaling receptor binding
tumor necrosis factor receptor binding

Displaying **all 5** entries
InterPro
Lymphotoxin-alpha
Tumour necrosis factor domain
Tumour necrosis factor, conserved site
Tumour necrosis factor-like domain superfamily
Tumour necrosis factor

Ortholog

Displaying entries **1 - 10** of 51 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	4049	9606_1:001b1f	HUMAN83916
Mus musculus	16992		MOUSE20700
Rattus norvegicus	25008		RATNO21778
Bos taurus	280845		BOVIN18802
Sus scrofa	407742		PIGXX31149
Canis lupus familiaris	607183		CANLF02542
Macaca mulatta	715425		MACMU33871
Equus caballus	100058321		HORSE19384
Oryctolagus cuniculus	100328931		RABIT02186
Callithrix jacchus	100397110		CALJA31722