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KCP

Summary

Gene Symbol

ORF4

Organism

Human gammaherpesvirus 8

External Links

NCBI Gene: 4961488
PubChem: 4961488

Annotation

Keyword

Disulfide bond
Glycoprotein
Host membrane
Inhibition of host complement factors by virus
Reference proteome
Repeat
Signal
Sushi
Transmembrane helix
Virion

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q2HRD4
F5HFG5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
virus-mediated perturbation of host defense response
evasion of host immune response via modulation of host complement system

GO Hierarchy

biological process

viral process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host [inference]

response to host defenses [inference]

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response [inference]

evasion of host immune response via modulation of host complement system

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane
host cell membrane
virion membrane

GO Hierarchy

cellular component

virion component [inference]

virion membrane

cellular anatomical entity [inference]

membrane

host cellular component [inference]

host cell part [inference]

host cell membrane

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level: Viruses
Group Name: Sushi/SCR/CCP domain

Displaying **all 2** entries
InterPro
Sushi/SCR/CCP domain
Sushi/SCR/CCP superfamily

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025

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