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C-C motif chemokine receptor 5

Summary

Gene Symbol

CCR5

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 497017
PubChem: 497017

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Sulfation
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2HJ17

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
inflammatory response	IEA	22301074
immune response	IEA	22301074 30032202
G protein-coupled receptor signaling pathway	IEA	22301074
positive regulation of cytosolic calcium ion concentration	IEA	30032202
calcium-mediated signaling	IEA	30032202

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cell motility [inference]

cell migration [inference]

cell chemotaxis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytoplasm
external side of plasma membrane	IEA	30032202
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
C-C chemokine receptor activity	IEA	22301074 30032202
chemokine (C-C motif) ligand 5 binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

chemokine binding [inference]

C-C chemokine binding [inference]

chemokine (C-C motif) ligand 5 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

G protein-coupled receptor activity [inference]

G protein-coupled chemoattractant receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **1 - 10** of 59 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	1234	HUMAN69649
Mus musculus	12774	MOUSE64342
Rattus norvegicus	117029	RATNO42203
Sus scrofa	414371	PIGXX03921
Pan troglodytes	450128	PANTR30964
Canis lupus familiaris	484789	CANLF07576
Felis catus	493769	FELCA04470
Macaca mulatta	735311	MACMU28253
Monodelphis domestica	100030002	MONDO34037
Equus caballus	100048935	HORSE12243