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leucine rich repeat transmembrane neuronal 4

Summary

Gene Symbol

Lrrtm4

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

500219

PubChem

500219

Alliance of Genome Resources

RGD:1560707

Annotation

Keyword

Cell membrane
Glycoprotein
Leucine-rich repeat
Postsynaptic cell membrane
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
B4F7C5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
regulation of presynaptic membrane organization	ISO
AMPA glutamate receptor clustering	ISO
synapse organization	IDA	19285470
regulation of synapse assembly	ISO
neurotransmitter-gated ion channel clustering	ISO

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering [inference]

neurotransmitter-gated ion channel clustering

glutamate receptor clustering [inference]

AMPA glutamate receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering [inference]

neurotransmitter-gated ion channel clustering

glutamate receptor clustering [inference]

AMPA glutamate receptor clustering

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering [inference]

neurotransmitter-gated ion channel clustering

glutamate receptor clustering [inference]

AMPA glutamate receptor clustering

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering [inference]

neurotransmitter-gated ion channel clustering

glutamate receptor clustering [inference]

AMPA glutamate receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering [inference]

neurotransmitter-gated ion channel clustering

glutamate receptor clustering [inference]

AMPA glutamate receptor clustering

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly

positive regulation of synapse assembly

regulation of presynaptic membrane organization

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
extracellular matrix	IBA
membrane	IEA
postsynaptic membrane	ISO
postsynaptic density membrane	IDA	23911103
AMPA glutamate receptor complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

cellular anatomical entity [inference]

extracellular space

membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse

ribbon synapse [inference]

photoreceptor ribbon synapse

external encapsulating structure [inference]

extracellular matrix

Displaying 1 entry
GO Term	Evidence Code	PMID
heparan sulfate proteoglycan binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

carbohydrate derivative binding [inference]

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

sulfur compound binding [inference]

heparan sulfate proteoglycan binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

leucine-rich repeat transmembrane neuronal protein 4

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat

Ortholog

Displaying entries **1 - 10** of 94 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	80059		HGNC:19411	HUMAN63467
Mus musculus	243499	10090_1:001e21	MGI:2389180	MOUSE48599
Pan troglodytes	470414			PANTR28006
Bos taurus	521137			BOVIN02609
Macaca mulatta	711411			MACMU08426
Ornithorhynchus anatinus	100079047			ORNAN22429
Pongo abelii	100173426			PONAB23288
Taeniopygia guttata	100228949			TAEGU13174
Callithrix jacchus	100393585			CALJA10943
Ailuropoda melanoleuca	100475003			AILME05155