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phospholipid phosphatase 2

Summary

Gene Symbol

PLPP2

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 504545
KEGG Gene ID: bta:504545
PubChem: 504545

Annotation

Keyword

Cell membrane
Endoplasmic reticulum
Endosome
Glycoprotein
Hydrolase
Lipid metabolism
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2HJ61	Lipid phosphate phosphohydrolase 2 PAP2-gamma Phosphatidate phosphohydrolase type 2c Phosphatidic acid phosphatase 2c

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ceramide metabolic process
sphingosine metabolic process
phospholipid dephosphorylation	IEA	30032202
signal transduction	IEA	30032202
phospholipid metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

dephosphorylation [inference]

phospholipid dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

phospholipid metabolic process

lipid modification [inference]

phospholipid dephosphorylation

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

phospholipid metabolic process

lipid modification [inference]

phospholipid dephosphorylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

phospholipid metabolic process

lipid modification [inference]

phospholipid dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process

cellular process [inference]

signal transduction

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

dephosphorylation [inference]

phospholipid dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

phospholipid metabolic process

lipid modification [inference]

phospholipid dephosphorylation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
early endosome membrane
caveola

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

early endosome membrane

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ceramide-1-phosphate phosphatase activity
phosphatidate phosphatase activity	IEA	30032202
sphingosine-1-phosphate phosphatase activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

lipid phosphatase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Lipid phosphate phosphohydrolase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
phospholipid dephosphorylation
phospholipid metabolic process

Displaying **all 3** entries
InterPro
Phosphatidate (PA) phosphatase-related
Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
Phosphatidic acid phosphatase type 2/haloperoxidase

KEGG BRITE Database

Orthology

K01080

Name

phosphatidate phosphatase [EC:3.1.3.4]

References

Rhea

RHEA:27429

H₂O + a 1,2-diacyl-sn-glycero-3-phosphate

a 1,2-diacyl-sn-glycerol + phosphate

Enzyme

3.1.3.4

PMID

RHEA:36239

H₂O + 1-O-alkyl-2-acyl-sn-glycero-3-phosphate

phosphate + 1-O-alkyl-2-acyl-sn-glycerol

Enzyme

3.1.3.4

Ortholog

Displaying entries **71 - 80** of **113** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Pygocentrus nattereri	108427214		PYGNA08931
Cyprinus carpio carpio	109069658		CYPCA70540
Cyprinus carpio carpio	109095638		CYPCA38162
Bos indicus	109561957	9915_0:0016ec
Phascolarctos cinereus	110223464		PHACI28455
Seriola dumerili	111226173		SERDU00396
Amphiprion ocellaris	111567714		AMPOC13334
Astatotilapia calliptera	113012286		ASTCA18066
Pseudonaja textilis	113435346		PSETE05804
Athene cunicularia	113489374		ATHCN21268

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements