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progestagen associated endometrial protein

Summary

Gene Symbol

PAEP

Organism

Homo sapiens (human)

External Links

NCBI Gene

5047

PubChem

5047

Alliance of Genome Resources

HGNC:8573

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disulfide bond
Glycoprotein
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A6XNE0
P09466	Placental protein 14 Pregnancy-associated endometrial alpha-2 globulin Progestagen-associated endometrial protein Progesterone-associated endometrial protein Zona-binding inhibitory factor-1
B2R4F9
B4E3C0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
apoptotic process	IDA	18996219
positive regulation of granulocyte macrophage colony-stimulating factor production	IDA	19945098
negative regulation of sperm capacitation	IMP	15883155
regulation of binding of sperm to zona pellucida	IDA	17192260

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of protein metabolic process [inference]

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of protein metabolic process [inference]

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

negative regulation of multicellular organismal process [inference]

negative regulation of sperm capacitation

negative regulation of reproductive process [inference]

negative regulation of sperm capacitation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

regulation of cell maturation [inference]

regulation of sperm capacitation [inference]

negative regulation of sperm capacitation

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

regulation of cell maturation [inference]

regulation of sperm capacitation [inference]

negative regulation of sperm capacitation

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of sperm capacitation

regulation of binding of sperm to zona pellucida

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

negative regulation of multicellular organismal process [inference]

negative regulation of sperm capacitation

regulation of sperm capacitation [inference]

negative regulation of sperm capacitation

regulation of reproductive process [inference]

regulation of sperm capacitation [inference]

negative regulation of sperm capacitation

negative regulation of reproductive process [inference]

negative regulation of sperm capacitation

regulation of binding of sperm to zona pellucida

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular region	IDA	12672671 3667877

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	25416956 29892012 31515488 32296183
small molecule binding	IEA

GO Hierarchy

molecular function

binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

beta-lactoglobulin

Functional Category

L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
retinol binding
small molecule binding

Displaying **all 5** entries
InterPro
Beta-lactoglobulin
Calycin
Lipocalin family conserved site
Lipocalin/cytosolic fatty-acid binding domain
Lipocalin

Ortholog

Displaying entries **1 - 10** of 16 in total

1

2

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Rattus norvegicus	5047	RGD:2293817
Bos taurus	280838		BOVIN03379
Sus scrofa	396596		PIGXX38838
Canis lupus familiaris	491263		CANLF19288
Canis lupus familiaris	491264		CANLF19290
Macaca mulatta	574318		MACMU13293
Pan troglodytes	748128		PANTR45218
Pongo abelii	100438880		PONAB35741
Sarcophilus harrisii	100924880		SARHA12662
Felis catus	101089907		FELCA30528

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements