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nonagouti

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

50518

PubChem

50518

Alliance of Genome Resources

MGI:87853

Annotation

Keyword

Disulfide bond
Glycoprotein
Knottin
Reference proteome
Secreted
Signal
Transmembrane helix
Viral envelope protein
Zinc-finger

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q03288	Agouti coat color protein Agouti switch protein
Q3TZL0
A0A510NUK5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 13 in total

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GO Term	Evidence Code	PMID
melanosome organization	IMP	9548375
melanosome organization	IBA
epigenetic regulation of gene expression	IMP	12601169
melanin biosynthetic process	IDA	8449404
melanin biosynthetic process	IMP	7665913

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic hydroxy compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

secondary metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

pigment metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

pigment biosynthetic process [inference]

melanin biosynthetic process

cellular metabolic process [inference]

generation of precursor metabolites and energy

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

cellular biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic cyclic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic hydroxy compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

organic hydroxy compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

cellular process [inference]

signal transduction [inference]

hormone-mediated signaling pathway

cellular metabolic process [inference]

generation of precursor metabolites and energy

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

cellular biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

pigment granule organization [inference]

melanosome organization

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

epigenetic regulation of gene expression

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

multicellular organismal process [inference]

behavior [inference]

feeding behavior [inference]

adult feeding behavior

adult behavior [inference]

adult feeding behavior

pigmentation

localization [inference]

establishment of localization [inference]

transport [inference]

pigment granule transport [inference]

melanosome transport

establishment of localization in cell [inference]

establishment of vesicle localization [inference]

establishment of pigment granule localization [inference]

establishment of melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

establishment of pigment granule localization [inference]

establishment of melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

organelle localization [inference]

vesicle localization [inference]

establishment of vesicle localization [inference]

establishment of pigment granule localization [inference]

establishment of melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

pigment granule localization [inference]

melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

establishment of pigment granule localization [inference]

establishment of melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of secondary metabolite biosynthetic process [inference]

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of secondary metabolic process [inference]

regulation of secondary metabolite biosynthetic process [inference]

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of cellular process [inference]

signal transduction [inference]

hormone-mediated signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of melanin biosynthetic process [inference]

positive regulation of melanin biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of melanin biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular space	ISS
extracellular space	ISO
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
neuropeptide hormone activity	IBA
protein binding	IPI	11137996
melanocortin receptor binding	IBA
melanocortin receptor binding	IPI	9454589
type 3 melanocortin receptor binding	IPI	9454589

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

neuropeptide receptor binding [inference]

melanocortin receptor binding

receptor ligand activity [inference]

hormone activity [inference]

neuropeptide hormone activity

neuropeptide activity [inference]

neuropeptide hormone activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity [inference]

neuropeptide hormone activity

neuropeptide activity [inference]

neuropeptide hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity [inference]

neuropeptide hormone activity

neuropeptide activity [inference]

neuropeptide hormone activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

endogenous retrovirus group K member 8 Pol protein-like

Functional Category

L: Replication, recombination and repair
V: Defense mechanisms
X: Mobilome: prophages, transposons

Displaying entries **1 - 10** of 11 in total

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Gene Ontology
DNA integration
RNA stem-loop binding
RNA-directed DNA polymerase activity
RNA-templated DNA biosynthetic process
endonuclease activity
hydrolase activity
metal ion binding
nuclease activity
nucleotidyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
DNA/RNA polymerase superfamily
Reverse transcriptase/Diguanylate cyclase domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 59 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	434	ZFIN:ZDB-GENE-060215-1	HUMAN56585
Rattus norvegicus	24152	ZFIN:ZDB-GENE-060215-1	RATNO26423
Danio rerio	50518	ZFIN:ZDB-GENE-060215-1
Bos taurus	404192		BOVIN05126
Sus scrofa	414439		PIGXX11615
Canis lupus familiaris	492296		CANLF09469
Felis catus	492297		FELCA06545
Macaca mulatta	709156		MACMU02165
Pan troglodytes	747368		PANTR24677
Monodelphis domestica	100032347		MONDO06578

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

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OrthoDB (Group)

International Collaboration

Acknowledgements