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solute carrier family 3 member 2

Summary

Gene Symbol

Slc3a2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

50567

PubChem

50567

Alliance of Genome Resources

RGD:3073

Annotation

Keyword

Amino-acid transport
Cell junction
Cell membrane
Disulfide bond
Glycoprotein
Isopeptide bond
Lysosome
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix
Ubl conjugation

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A6HZS0	4F2 cell-surface antigen heavy chain Solute carrier family 3 member 2
Q794F9	4F2 cell-surface antigen heavy chain Solute carrier family 3 member 2
A0A0H2UHQ0	4F2 cell-surface antigen heavy chain Solute carrier family 3 member 2
A6HZS2	4F2 cell-surface antigen heavy chain Solute carrier family 3 member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 40 in total

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GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
response to muscle activity	IEP	24016666
neutral amino acid transport	IMP	9726963
isoleucine transport	ISO
isoleucine transport	IEA

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to activity [inference]

response to muscle activity

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

response to nitrogen compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

localization [inference]

establishment of localization [inference]

transport [inference]

hormone transport [inference]

thyroid hormone transport

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

aromatic amino acid transport [inference]

basic amino acid transport [inference]

histidine transport [inference]

L-histidine transport

branched-chain amino acid transport [inference]

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

valine transport

neutral amino acid transport

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

alanine transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-amino acid transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-histidine transport

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

phenylalanine transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

aromatic amino acid transport [inference]

basic amino acid transport [inference]

histidine transport [inference]

L-histidine transport

branched-chain amino acid transport [inference]

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

valine transport

neutral amino acid transport

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

alanine transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-amino acid transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-histidine transport

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

phenylalanine transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

nitrogen compound transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

aromatic amino acid transport [inference]

basic amino acid transport [inference]

histidine transport [inference]

L-histidine transport

branched-chain amino acid transport [inference]

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

valine transport

neutral amino acid transport

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

alanine transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-amino acid transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-histidine transport

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

phenylalanine transport

sulfur compound transport [inference]

sulfur amino acid transport [inference]

methionine transport

import into cell [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alanine import across plasma membrane

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

thyroid hormone transport

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
nucleoplasm	IEA
lysosomal membrane	IEA
plasma membrane	ISS
plasma membrane	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

amino acid transport complex

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

plasma membrane region [inference]

cell junction [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

cell body [inference]

neuronal cell body

cell pole [inference]

apical pole of neuron

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GO Term	Evidence Code	PMID
double-stranded RNA binding	ISO
double-stranded RNA binding	IEA
neutral L-amino acid secondary active transmembrane transporter activity
aromatic amino acid transmembrane transporter activity	ISO
aromatic amino acid transmembrane transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity

neutral L-amino acid transmembrane transporter activity

alanine transmembrane transporter activity [inference]

L-alanine transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

branched-chain amino acid transmembrane transporter activity [inference]

L-leucine transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity

neutral L-amino acid transmembrane transporter activity

alanine transmembrane transporter activity [inference]

L-alanine transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

branched-chain amino acid transmembrane transporter activity [inference]

L-leucine transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

neutral L-amino acid secondary active transmembrane transporter activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

exogenous protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

double-stranded RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

4F2 cell-surface antigen heavy chain

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 5** entries
Gene Ontology
L-alanine import across plasma membrane
L-alanine transmembrane transporter activity
L-leucine transmembrane transporter activity
aromatic amino acid transmembrane transporter activity
phenylalanine transport

Displaying **all 5** entries
InterPro
Amino acid transporter heavy chain SLC3A2
Glycoside hydrolase superfamily
Glycosyl hydrolase, all-beta
Glycosyl hydrolase, family 13, catalytic domain
Solute carrier family 3 member 2, N-terminal domain

Ortholog

Displaying entries **1 - 10** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	6519	WB:WBGene00000225
Homo sapiens	6520	Xenbase:XB-GENE-1009245	HUMAN06694
Mus musculus	17254	Xenbase:XB-GENE-1009245	MOUSE25789
Caenorhabditis elegans	20532	WB:WBGene00000225
Caenorhabditis elegans	29484	WB:WBGene00000225
Caenorhabditis elegans	35824	WB:WBGene00000225
Caenorhabditis elegans	35825	WB:WBGene00000225
Caenorhabditis elegans	35826	WB:WBGene00000225
Xenopus tropicalis	50567	Xenbase:XB-GENE-1009245
Caenorhabditis elegans	175125	WB:WBGene00000225

GlyTouCan

GlyComb

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OrthoDB (Group)

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Acknowledgements