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anoctamin 7

Summary

Gene Symbol

ANO7

Organism

Homo sapiens (human)

External Links

NCBI Gene

50636

PubChem

50636

Alliance of Genome Resources

HGNC:31677

Annotation

Keyword

Alternative splicing
Cell junction
Cell membrane
Cytoplasm
Endoplasmic reticulum
Glycoprotein
Lipid transport
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6IWH7	Dresden transmembrane protein of the prostate IPCA-5 New gene expressed in prostate Prostate cancer-associated protein 5 Transmembrane protein 16G

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
chloride transmembrane transport	IBA IDA	22946059
ion transmembrane transport	TAS
monoatomic ion transmembrane transport	TAS
calcium activated phospholipid scrambling	IBA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

organic substance transport [inference]

lipid transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling

organophosphate ester transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling

Displaying **all 4** entries
GO Term	Evidence Code	PMID
anchoring junction	IEA
plasma membrane	IBA IDA TAS	14981236 22946059
endoplasmic reticulum	IDA	22075693
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein dimerization activity	IEA
intracellular calcium activated chloride channel activity	IDA	21984732 22075693 22946059
chloride channel activity	IBA TAS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

salt transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

binding [inference]

protein binding [inference]

protein dimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

anoctamin

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
chloride channel activity

Displaying **all 2** entries
InterPro
Anoctamin, transmembrane domain
Anoctamin

Ortholog

Displaying entries **11 - 20** of 35 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Pan paniscus	100994471	9597_0:000dc2
Felis catus	101096590		FELCA18587
Gorilla gorilla gorilla	101126127	9595_0:000d3e
Mustela putorius furo	101680322		MUSPF17052
Lepisosteus oculatus	102691435		LEPOC04480
Astyanax mexicanus	103022406		ASTMX02270
Chlorocebus sabaeus	103218239		CHLSB01792
Cynoglossus semilaevis	103378393		CYNSE23175
Nannospalax galili	103730843		NANGA13382
Macaca nemestrina	105473766		MACNE18609