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periostin, osteoblast specific factor

Summary

Gene Symbol

Postn

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

50706

PubChem

50706

Alliance of Genome Resources

MGI:1926321

Annotation

Keyword

Alternative splicing
Cell adhesion
Disulfide bond
Extracellular matrix
Gamma-carboxyglutamic acid
Glycoprotein
Golgi apparatus
Heparin-binding
Reference proteome
Repeat
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A097BW21
A0A097BW18
Q62009	Osteoblast-specific factor 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 29 in total

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GO Term	Evidence Code	PMID
response to hypoxia	IEA
negative regulation of cell-matrix adhesion	ISO
negative regulation of cell-matrix adhesion	IEA
regulation of systemic arterial blood pressure	ISO
regulation of systemic arterial blood pressure	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

cell adhesion

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

cellular response to chemical stimulus [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to oxygen-containing compound [inference]

cellular response to ketone [inference]

cellular response to vitamin K

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

developmental process [inference]

anatomical structure development [inference]

tissue development

regeneration [inference]

tissue regeneration [inference]

bone regeneration

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

developmental growth [inference]

tissue regeneration [inference]

bone regeneration

developmental cell growth [inference]

neuron projection extension

developmental growth involved in morphogenesis [inference]

neuron projection extension

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to external stimulus [inference]

response to mechanical stimulus

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

response to vitamin [inference]

response to vitamin K [inference]

cellular response to vitamin K

cellular response to vitamin [inference]

cellular response to vitamin K

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

response to abiotic stimulus [inference]

response to mechanical stimulus

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

response to transforming growth factor beta [inference]

cellular response to transforming growth factor beta stimulus

response to fibroblast growth factor [inference]

cellular response to fibroblast growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

response to activity [inference]

response to muscle activity

response to chemical [inference]

response to nutrient [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

response to vitamin [inference]

response to vitamin K [inference]

cellular response to vitamin K

cellular response to vitamin [inference]

cellular response to vitamin K

response to organic substance [inference]

response to organic cyclic compound [inference]

response to estradiol

response to lipid [inference]

response to estradiol

response to cytokine [inference]

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

response to ketone [inference]

response to vitamin K [inference]

cellular response to vitamin K

cellular response to ketone [inference]

cellular response to vitamin K

cellular response to chemical stimulus [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to oxygen-containing compound [inference]

cellular response to ketone [inference]

cellular response to vitamin K

response to oxygen-containing compound [inference]

response to estradiol

response to ketone [inference]

response to vitamin K [inference]

cellular response to vitamin K

cellular response to ketone [inference]

cellular response to vitamin K

cellular response to oxygen-containing compound [inference]

cellular response to ketone [inference]

cellular response to vitamin K

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

cellular response to chemical stimulus [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin K

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to oxygen-containing compound [inference]

cellular response to ketone [inference]

cellular response to vitamin K

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of smooth muscle cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of smooth muscle cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell-substrate adhesion [inference]

regulation of substrate adhesion-dependent cell spreading [inference]

negative regulation of substrate adhesion-dependent cell spreading

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of smooth muscle cell migration

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of smooth muscle cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of smooth muscle cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IBA
extracellular space	HDA	24006456
trans-Golgi network	ISO
trans-Golgi network	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

cell junction [inference]

synapse [inference]

neuromuscular junction

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular matrix structural constituent	RCA	22159717 28071719
heparin binding	IDA	7663166
metal ion binding	ISS
metal ion binding	ISO
cell adhesion molecule binding	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding [inference]

cell adhesion molecule binding

ion binding [inference]

cation binding [inference]

metal ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

fasciclin-1

Functional Category

C: Energy production and conversion
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cell adhesion molecule binding
extracellular matrix organization

Displaying **all 2** entries
InterPro
FAS1 domain superfamily
FAS1 domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080010	bone structure disease	Alliance of Genome Resources
DOID:1474	aggressive periodontitis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 84 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	7045	SGD:S000003991
Homo sapiens	10631	Xenbase:XB-GENE-478502	HUMAN16808
Xenopus tropicalis	42025	Xenbase:XB-GENE-478502
Xenopus tropicalis	50706	Xenbase:XB-GENE-478502
Bos taurus	281960		BOVIN03763
Danio rerio	337176		DANRE08674
Rattus norvegicus	361945		RATNO23158
Pan troglodytes	452543		PANTR07624
Canis lupus familiaris	477298		CANLF09797
Macaca mulatta	695528		MACMU16924

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements