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glyoxalase I

Summary

Gene Symbol

GLO1

Organism

Leishmania infantum JPCM5

External Links

NCBI Gene: 5073200
KEGG Gene ID: lif:LINJ_35_3060
PubChem: 5073200

Annotation

Keyword

Lyase
Metal-binding
Reference proteome
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
A4IBI9	Glyoxalase I

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

small molecule catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic substance catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

small molecule catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic substance catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic hydroxy compound metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying **all 2** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA	22301074
lactoylglutathione lyase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-sulfur lyase activity [inference]

lactoylglutathione lyase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01759

Name

lactoylglutathione lyase [EC:4.4.1.5]

References

8824231

Rhea

RHEA:19069

(R)-S-lactoylglutathione

methylglyoxal + glutathione

Enzyme

4.4.1.5

PMID

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements