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C-P62-6K-E1 polyprotein

Summary

Gene Symbol

GETV_gp2

Organism

Getah virus

External Links

NCBI Gene: 5075853
PubChem: 5075853

Annotation

Keyword

3D-structure
Cleavage on pair of basic residues
Disulfide bond
Fusion of virus membrane with host endosomal membrane
Glycoprotein
Host Golgi apparatus
Host cell membrane
Host cytoplasm
Host endoplasmic reticulum
Host nucleus
Palmitate
RNA-binding
Reference proteome
Serine protease
T=4 icosahedral capsid protein
Transmembrane helix
Viral attachment to host entry receptor
Viral ion channel

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5Y388	p130

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proteolysis
virion attachment to host cell
fusion of virus membrane with host endosome membrane
suppression by virus of host toll-like receptor signaling pathway
viral entry into host cell

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

viral process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

membrane fusion involved in viral entry into host cell [inference]

fusion of virus membrane with host endosome membrane

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation of host signal transduction pathway [inference]

symbiont-mediated suppression of host signal transduction pathway [inference]

symbiont-mediated suppression of host toll-like receptor signal transduction [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation of signal transduction in another organism [inference]

perturbation of host signal transduction pathway [inference]

symbiont-mediated suppression of host signal transduction pathway [inference]

symbiont-mediated suppression of host toll-like receptor signal transduction [inference]

suppression by virus of host toll-like receptor signaling pathway

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation of host signal transduction pathway [inference]

symbiont-mediated suppression of host signal transduction pathway [inference]

symbiont-mediated suppression of host toll-like receptor signal transduction [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

adhesion of symbiont to host [inference]

adhesion of symbiont to host cell [inference]

virion attachment to host cell

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression by virus of host toll-like receptor signaling pathway

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
membrane
host cell plasma membrane
host cell cytoplasm
T=4 icosahedral viral capsid
host cell nucleus

GO Hierarchy

cellular component

virion component [inference]

viral capsid [inference]

icosahedral viral capsid [inference]

T=4 icosahedral viral capsid

virion membrane

cellular anatomical entity [inference]

membrane

host cellular component [inference]

host cell part [inference]

host cell membrane [inference]

host cell plasma membrane

host intracellular part [inference]

host cell cytoplasm

host intracellular organelle [inference]

host intracellular membrane-bounded organelle [inference]

host cell nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
RNA binding
serine-type endopeptidase activity
structural molecule activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

structural molecule activity

binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

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Last updated: December 8, 2025

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