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potassium two pore domain channel subfamily K member 4

Summary

Gene Symbol

KCNK4

Organism

Homo sapiens (human)

External Links

NCBI Gene

50801

PubChem

50801

Alliance of Genome Resources

HGNC:6279

JoGo

KCNK4

TogoVar

KCNK4

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell projection
Disease variant
Disulfide bond
Epilepsy
Glycoprotein
Intellectual disability
Metal-binding
Potassium channel
Proteomics identification
Reference proteome
Transmembrane helix
Voltage-gated channel

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q2YDA1	TWIK-related arachidonic acid-stimulated potassium channel protein
Q9NYG8	TWIK-related arachidonic acid-stimulated potassium channel protein Two pore potassium channel KT4.1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
potassium ion transport	TAS	10767409
memory	IEA
neuronal action potential	ISS
sensory perception of pain	ISS
stabilization of membrane potential

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to fatty acid

cellular response to arachidonic acid

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid

cellular response to arachidonic acid

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular response to pH [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

cognition [inference]

learning or memory [inference]

memory

behavior [inference]

learning or memory [inference]

memory

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

cellular response to temperature stimulus

response to pH [inference]

response to alkaline pH [inference]

cellular response to alkaline pH

response to acidic pH [inference]

cellular response to acidic pH

cellular response to pH [inference]

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular response to pH [inference]

response to chemical [inference]

response to organic substance [inference]

response to lipid [inference]

response to fatty acid [inference]

cellular response to fatty acid

cellular response to arachidonic acid

response to arachidonic acid [inference]

cellular response to arachidonic acid

cellular response to lipid [inference]

cellular response to fatty acid

cellular response to arachidonic acid

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to fatty acid

cellular response to arachidonic acid

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to fatty acid

cellular response to arachidonic acid

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid

cellular response to arachidonic acid

response to oxygen-containing compound [inference]

response to fatty acid [inference]

cellular response to fatty acid

cellular response to arachidonic acid

response to arachidonic acid [inference]

cellular response to arachidonic acid

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid

cellular response to arachidonic acid

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

detection of stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to fatty acid

cellular response to arachidonic acid

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid

cellular response to arachidonic acid

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular response to pH [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane potential [inference]

action potential [inference]

neuronal action potential

stabilization of membrane potential

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	TAS
plasma membrane	IMP	22282805
plasma membrane	IBA
node of Ranvier	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

node of Ranvier

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
potassium channel activity	IDA	22282805
protein binding	IPI	32296183
outward rectifier potassium channel activity	IDA	26919430
outward rectifier potassium channel activity	IBA
potassium ion leak channel activity	IDA	26919430