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calreticulin 3

Summary

Gene Symbol

CALR3

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 508555
KEGG Gene ID: bta:508555
PubChem: 508555

Annotation

Keyword

Chaperone
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Lectin
Metal-binding
Reference proteome
Repeat
Signal
Spermatogenesis
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q2TBR8	Calsperin
F1MTN0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein folding	IEA	22301074 30032202
spermatogenesis
cell differentiation
ERAD pathway

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular process [inference]

protein folding

cellular developmental process [inference]

cell differentiation

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

cellular developmental process [inference]

cell differentiation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

ERAD pathway

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202
endoplasmic reticulum lumen
endoplasmic reticulum	IEA	22301074 30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA	22301074 30032202
unfolded protein binding	IEA	22301074 30032202
carbohydrate binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

unfolded protein binding

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Calreticulin

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
calcium ion binding
unfolded protein binding

Displaying **all 4** entries
InterPro
Calreticulin/calnexin, P domain superfamily
Calreticulin/calnexin, conserved site
Calreticulin/calnexin
Concanavalin A-like lectin/glucanase domain superfamily

KEGG BRITE Database

Orthology

K10098

Name

calreticulin 3

References

21590275

Ortholog

Displaying entries **21 - 30** of 60 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mustela putorius furo	101684458			MUSPF10003
Ictidomys tridecemlineatus	101973655			ICTTR00129
Chinchilla lanigera	102025612			CHILA22255
Capra hircus	102178617	9925_0:001614		CAPHI28445
Bos mutus	102265726	72004_1:002e3a
Bubalus bubalis	102411060	89462_0:00287f
Myotis lucifugus	102439045			MYOLU11944
Camelus ferus	102520393	419612_0:003f3f
Vicugna pacos	102544291	30538_0:002c13
Physeter catodon	102973338	9755_0:0002f1

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024