GlyCosmos Portal

Submissions

fibroblast activation protein alpha

Summary

Gene Symbol

FAP

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 508882
PubChem: 508882

Annotation

Keyword

Angiogenesis
Apoptosis
Cell adhesion
Cell junction
Cell membrane
Cell projection
Cleavage on pair of basic residues
Coiled coil
Direct protein sequencing
Disulfide bond
Glycoprotein
Reference proteome
Secreted
Serine protease
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A5D7B7	Dipeptidyl peptidase FAP Fibroblast activation protein alpha Gelatine degradation protease FAP Integral membrane serine protease Post-proline cleaving enzyme Serine integral membrane protease Surface-expressed protease Z-Pro-prolinal insensitive peptidase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
proteolysis	IEA	22301074
apoptotic process
cell adhesion
angiogenesis

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

cellular process [inference]

cell adhesion

cell death [inference]

programmed cell death [inference]

apoptotic process

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
anchoring junction
ruffle membrane
plasma membrane
extracellular region
lamellipodium membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

cell junction [inference]

anchoring junction

leading edge membrane [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
dipeptidyl-peptidase activity	IEA	30032202
serine-type endopeptidase activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

exopeptidase activity [inference]

dipeptidyl-peptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

exopeptidase activity [inference]

dipeptidyl-peptidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

peptidase

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
dipeptidyl-peptidase activity
proteolysis
serine-type peptidase activity

Displaying **all 3** entries
InterPro
Alpha/Beta hydrolase fold
Dipeptidylpeptidase IV, N-terminal domain
Peptidase S9, prolyl oligopeptidase, catalytic domain

Ortholog

Displaying entries **1 - 10** of 82 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Orthologous MAtrix
Homo sapiens	2191	HUMAN65259
Mus musculus	14089	MOUSE31233
Rattus norvegicus	192203	RATNO27446
Pan troglodytes	459691	PANTR28982
Canis lupus familiaris	608176	CANLF13911
Macaca mulatta	701541	MACMU07210
Monodelphis domestica	100022372	MONDO23185
Equus caballus	100051480	HORSE13781
Ornithorhynchus anatinus	100082270	ORNAN27386
Taeniopygia guttata	100228501	TAEGU28667