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Guidelines

MIRAGE

mitochondrial ribosomal protein L2

Summary

Gene Symbol

MRPL2

Organism

Homo sapiens (human)

External Links

NCBI Gene

51069

PubChem

51069

Alliance of Genome Resources

HGNC:14056

Annotation

Keyword

3D-structure
Mitochondrion
Reference proteome
Ribosomal protein
Transit peptide

Proteins

Displaying **all 2** entries
UniProt	Protein Name
C9IY40
Q5T653	39S ribosomal protein L2, mitochondrial

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrial translation	NAS	27023846
mitochondrial translation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

protein metabolic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

primary metabolic process [inference]

protein metabolic process [inference]

translation [inference]

mitochondrial translation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

protein metabolic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

protein metabolic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleoplasm	IDA
mitochondrion	IDA	28892042
mitochondrion	HTP	34800366
mitochondrial inner membrane	NAS	27023846
mitochondrial inner membrane	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

mitochondrial protein-containing complex [inference]

mitochondrial large ribosomal subunit

ribonucleoprotein complex [inference]

ribosomal subunit [inference]

large ribosomal subunit [inference]

organellar large ribosomal subunit [inference]

mitochondrial large ribosomal subunit

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
RNA binding	IBA
RNA binding	HDA	22658674 22681889
structural constituent of ribosome	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of ribosome

binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

L2

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cytoplasmic translation
mitochondrial translation

Displaying **all 7** entries
InterPro
Large ribosomal subunit protein uL2, C-terminal
Large ribosomal subunit protein uL2, RNA-binding domain
Large ribosomal subunit protein uL2, domain 2
Large ribosomal subunit protein uL2, domain 3
Large ribosomal subunit protein uL2
Nucleic acid-binding, OB-fold
Translation protein SH3-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	27398		MOUSE22489
Danio rerio	51069	ZFIN:ZDB-GENE-050809-12
Rattus norvegicus	301240		RATNO43440
Canis lupus familiaris	474908		CANLF02766
Bos taurus	514403		BOVIN18526
Danio rerio	571648		DANRE06435
Macaca mulatta	698483		MACMU34697
Macaca mulatta	699545		MACMU34697
Monodelphis domestica	100010957		MONDO11257
Equus caballus	100054974		HORSE19256

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.1

Last updated: April 7, 2025