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Guidelines

MIRAGE

SID1 transmembrane family member 2

Summary

Gene Symbol

SIDT2

Organism

Homo sapiens (human)

External Links

NCBI Gene

51092

PubChem

51092

Alliance of Genome Resources

HGNC:24272

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
DNA-binding
Direct protein sequencing
Glycoprotein
Lysosome
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Signal
Transmembrane helix
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8NBJ9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

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GO Term	Evidence Code	PMID
cell morphogenesis	IEA
type B pancreatic cell development	IEA
RNA catabolic process	ISS
response to glucose	IEA
glucose homeostasis	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular process [inference]

cell population proliferation [inference]

epithelial cell proliferation [inference]

type B pancreatic cell proliferation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

glandular epithelial cell development [inference]

type B pancreatic cell development

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

anatomical structure development [inference]

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

glandular epithelial cell development [inference]

type B pancreatic cell development

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

glandular epithelial cell development [inference]

type B pancreatic cell development

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport

establishment of RNA localization [inference]

RNA transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of peptide secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of protein secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of protein transport [inference]

regulation of protein secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of protein secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
lysosome	IDA	28277980
lysosome	IBA
lysosomal membrane	IDA	17897319
plasma membrane	IDA	28277980
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
DNA binding	IEA
double-stranded RNA binding	IBA
AP-2 adaptor complex binding	ISS
AP-1 adaptor complex binding	ISS
nucleic acid transmembrane transporter activity	ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

nucleobase-containing compound transmembrane transporter activity [inference]

nucleic acid transmembrane transporter activity

RNA transmembrane transporter activity

macromolecule transmembrane transporter activity [inference]

nucleic acid transmembrane transporter activity

RNA transmembrane transporter activity

binding [inference]

protein-containing complex binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

RNA binding [inference]

double-stranded RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

SID1 transmembrane family member

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
RNA transmembrane transporter activity
double-stranded RNA binding

Displaying 1 entry
InterPro
SID1 transmembrane family

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025