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protein tyrosine phosphatase receptor type F

Summary

Gene Symbol

PTPRF

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 512072
PubChem: 512072

Annotation

Keyword

Cell adhesion
Disulfide bond
Glycoprotein
Heparin-binding
Immunoglobulin domain
Phosphoprotein
Protein phosphatase
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A7MBJ4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
peptidyl-tyrosine dephosphorylation
cell migration
negative regulation of receptor binding
synaptic membrane adhesion
protein dephosphorylation	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

synaptic membrane adhesion

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

cell motility [inference]

cell migration

biological regulation [inference]

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of binding [inference]

negative regulation of protein binding [inference]

negative regulation of receptor binding

regulation of binding [inference]

regulation of protein binding [inference]

negative regulation of protein binding [inference]

negative regulation of receptor binding

regulation of receptor binding [inference]

negative regulation of receptor binding

negative regulation of binding [inference]

negative regulation of protein binding [inference]

negative regulation of receptor binding

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IEA	22301074
heparin binding
protein tyrosine phosphatase activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

protein binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Tyrosine phosphatase

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
dephosphorylation
protein tyrosine phosphatase activity

Displaying **all 5** entries
InterPro
Protein-tyrosine phosphatase, active site
Protein-tyrosine phosphatase, catalytic
Protein-tyrosine phosphatase-like
Tyrosine-specific protein phosphatase, PTPase domain
Tyrosine-specific protein phosphatases domain

Ortholog

Displaying entries **1 - 10** of 95 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	5792	HUMAN49325
Mus musculus	19268	MOUSE41361
Danio rerio	140819	DANRE38220
Rattus norvegicus	360406	RATNO34614
Pan troglodytes	456828	PANTR20853
Canis lupus familiaris	475389	CANLF04108
Macaca mulatta	701160	MACMU21537
Danio rerio	799867	DANRE28745
Ornithorhynchus anatinus	100078392	ORNAN09807
Taeniopygia guttata	100222172	TAEGU29332