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protein tyrosine phosphatase receptor type F

Summary

Gene Symbol

PTPRF

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 512072
PubChem: 512072

Annotation

Keyword

Cell adhesion
Disulfide bond
Glycoprotein
Heparin-binding
Immunoglobulin domain
Phosphoprotein
Protein phosphatase
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A7MBJ4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cell migration
peptidyl-tyrosine dephosphorylation
synaptic membrane adhesion
negative regulation of receptor binding
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

synaptic membrane adhesion

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cell motility [inference]

cell migration

biological regulation [inference]

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of binding [inference]

negative regulation of protein binding [inference]

negative regulation of receptor binding

regulation of binding [inference]

regulation of protein binding [inference]

negative regulation of protein binding [inference]

negative regulation of receptor binding

regulation of receptor binding [inference]

negative regulation of receptor binding

negative regulation of binding [inference]

negative regulation of protein binding [inference]

negative regulation of receptor binding

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane
receptor complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity	IEA	22301074
protein binding	IEA	22301074
heparin binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

protein binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Receptor-type tyrosine-protein phosphatase S

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
dephosphorylation
hydrolase activity
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity

Displaying entries **1 - 10** of 13 in total

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InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Protein-tyrosine phosphatase, active site
Protein-tyrosine phosphatase, catalytic

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	5792	HUMAN49325
Mus musculus	19268	MOUSE41361
Danio rerio	140819	DANRE38220
Rattus norvegicus	360406	RATNO34614
Pan troglodytes	456828	PANTR20853
Canis lupus familiaris	475389	CANLF04108
Macaca mulatta	701160	MACMU21537
Danio rerio	799867	DANRE28745
Ornithorhynchus anatinus	100078392	ORNAN09807
Taeniopygia guttata	100222172	TAEGU29332