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glutamate decarboxylase 2

Summary

Gene Symbol

GAD2

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 512459
KEGG Gene ID: bta:512459
PubChem: 512459

Annotation

Keyword

Cell membrane
Cell projection
Cytoplasmic vesicle
Decarboxylase
Golgi apparatus
Palmitate
Pyridoxal phosphate
Reference proteome
Synapse

Proteins

Displaying 1 entry
UniProt	Protein Name
F1N6X2	65 kDa glutamic acid decarboxylase Glutamate decarboxylase 65 kDa isoform

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
glutamate decarboxylation to succinate	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid metabolic process [inference]

succinate metabolic process [inference]

glutamate decarboxylation to succinate

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid metabolic process [inference]

succinate metabolic process [inference]

glutamate decarboxylation to succinate

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid metabolic process [inference]

succinate metabolic process [inference]

glutamate decarboxylation to succinate

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid metabolic process [inference]

succinate metabolic process [inference]

glutamate decarboxylation to succinate

glutamate metabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

dicarboxylic acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process [inference]

glutamate decarboxylation to succinate

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glutamate decarboxylase activity	IEA	30032202
pyridoxal phosphate binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity [inference]

glutamate decarboxylase activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

glutamate decarboxylase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 4** entries
Gene Ontology
carbon-carbon lyase activity
carboxylic acid metabolic process
lyase activity
pyridoxal phosphate binding

Displaying **all 3** entries
InterPro
Pyridoxal phosphate-dependent decarboxylase
Pyridoxal phosphate-dependent transferase, major domain
Pyridoxal phosphate-dependent transferase

KEGG BRITE Database

Orthology

K01580

Name

glutamate decarboxylase [EC:4.1.1.15]

References

Rhea

H⁺ + L-glutamate

CO₂ + 4-aminobutanoate

Enzyme

4.1.1.15

PMID

Ortholog

Displaying entries **21 - 30** of 87 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Cavia porcellus	100734029			CAVPO22431
Cricetulus griseus	100757642			CRIGR21938
Sarcophilus harrisii	100920746			SARHA16580
Otolemur garnettii	100965286			OTOGA14530
Papio anubis	101006779			PAPAN03143
Saimiri boliviensis boliviensis	101034327			SAIBB17845
Felis catus	101082244			FELCA17400
Ovis aries	101106448	9940_0:0032bc		SHEEP04188
Gorilla gorilla gorilla	101141671			GORGO01400
Tursiops truncatus	101340132	9739_0:000824		TURTR01566

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Last updated: December 9, 2024