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GDP-mannose pyrophosphorylase B

Summary

Gene Symbol

GMPPB

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 514161
KEGG Gene ID: bta:514161
PubChem: 514161

Annotation

Keyword

Cytoplasm
GTP-binding
Nucleotidyltransferase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2YDJ9	GDP-mannose pyrophosphorylase B GTP-mannose-1-phosphate guanylyltransferase beta

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
GDP-mannose biosynthetic process	IEA	22301074 30032202
protein glycosylation	IEA	30032202
cell wall mannoprotein biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

mannoprotein metabolic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

mannoprotein metabolic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

protein modification process [inference]

protein glycosylation

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

mannoprotein metabolic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

cell wall macromolecule metabolic process [inference]

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

mannoprotein metabolic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

mannoprotein metabolic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

mannoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

cell wall glycoprotein biosynthetic process [inference]

cell wall mannoprotein biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mannose-1-phosphate guanylyltransferase (GTP) activity	IEA	22301074 30032202
GTP binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

guanylyltransferase activity [inference]

mannose-1-phosphate guanylyltransferase (GTP) activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Glucose-1-phosphate adenylyltransferase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 6** entries
Gene Ontology
GDP-mannose biosynthetic process
GTP binding
mannose-1-phosphate guanylyltransferase (GTP) activity
nucleotide binding
nucleotidyltransferase activity
transferase activity

Displaying **all 4** entries
InterPro
Hexapeptide repeat
Mannose-1-phosphate guanyltransferase, N-terminal domain
Nucleotide-diphospho-sugar transferases
Nucleotidyl transferase domain

KEGG BRITE Database

Orthology

K00966

Name

mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]

References

11082198

Rhea

H⁺ + GTP + α-D-mannose 1-phosphate

diphosphate + GDP-α-D-mannose

Enzyme

2.7.7.13

PMID

Ortholog

Displaying entry **91 - 91** of 91 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Hippopotamus amphibius kiboko	130834586	575201_0:0041ca

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024