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prenylcysteine oxidase 1

Summary

Gene Symbol

PCYOX1

Organism

Homo sapiens (human)

External Links

NCBI Gene

51449

PubChem

51449

Alliance of Genome Resources

HGNC:20588

Annotation

Keyword

Alternative splicing
Direct protein sequencing
FAD
Glycoprotein
Lysosome
Oxidoreductase
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UHG3	Prenylcysteine lyase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
prenylated protein catabolic process	NAS	9287348
prenylated protein catabolic process	IDA	10585463
prenylated protein catabolic process	IBA
prenylcysteine catabolic process	IDA	11078725 12186880

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

prenylcysteine metabolic process [inference]

prenylcysteine catabolic process

cellular modified amino acid catabolic process [inference]

prenylcysteine catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

prenylated protein catabolic process

organonitrogen compound catabolic process [inference]

cellular modified amino acid catabolic process [inference]

prenylcysteine catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

prenylated protein catabolic process

organonitrogen compound catabolic process [inference]

cellular modified amino acid catabolic process [inference]

prenylcysteine catabolic process

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

prenylcysteine metabolic process [inference]

prenylcysteine catabolic process

cellular modified amino acid catabolic process [inference]

prenylcysteine catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

prenylated protein catabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

prenylated protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

prenylated protein catabolic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

prenylcysteine metabolic process [inference]

prenylcysteine catabolic process

cellular modified amino acid catabolic process [inference]

prenylcysteine catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

prenylated protein catabolic process

organonitrogen compound catabolic process [inference]

cellular modified amino acid catabolic process [inference]

prenylcysteine catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

prenylated protein catabolic process

organonitrogen compound catabolic process [inference]

cellular modified amino acid catabolic process [inference]

prenylcysteine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

prenylcysteine metabolic process [inference]

prenylcysteine catabolic process

cellular modified amino acid catabolic process [inference]

prenylcysteine catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
lysosome	IDA	10585463
very-low-density lipoprotein particle	IDA	17154273
extracellular exosome	HDA	19056867

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex [inference]

lipoprotein particle [inference]

plasma lipoprotein particle [inference]

triglyceride-rich plasma lipoprotein particle [inference]

very-low-density lipoprotein particle

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
prenylcysteine oxidase activity	IDA	10585463 11078725 12186880
prenylcysteine oxidase activity	IBA
protein binding	IPI	32296183 33961781
FAD binding	IDA	11078725
farnesylcysteine lyase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor [inference]

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Prenylcysteine

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
oxidoreductase activity
prenylated protein catabolic process
prenylcysteine catabolic process
prenylcysteine oxidase activity

Displaying **all 3** entries
InterPro
FAD/NAD(P)-binding domain superfamily
Prenylcysteine lyase
Prenylcysteine oxidase

Ortholog

Displaying entries **1 - 10** of 70 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	51449	Xenbase:XB-GENE-1002891
Mus musculus	66881	Xenbase:XB-GENE-1002891	MOUSE50077
Rattus norvegicus	246302	Xenbase:XB-GENE-1002891	RATNO31658
Pan troglodytes	470398		PANTR27837
Canis lupus familiaris	481418		CANLF01930
Danio rerio	550289		DANRE01476
Macaca mulatta	710068		MACMU08228
Monodelphis domestica	100032803		MONDO05592
Equus caballus	100060594		HORSE09953
Ornithorhynchus anatinus	100091365		ORNAN22320