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charged multivesicular body protein 5

Summary

Gene Symbol

CHMP5

Organism

Homo sapiens (human)

External Links

NCBI Gene

51510

PubChem

51510

Alliance of Genome Resources

HGNC:26942

Annotation

Keyword

3D-structure
Alternative splicing
Coiled coil
Cytoplasm
Endosome
Lipoprotein
Membrane
Phosphoprotein
Protein transport
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NZZ3	Chromatin-modifying protein 5 SNF7 domain-containing protein 2 Vacuolar protein sorting-associated protein 60

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
plasma membrane repair	IDA	24482116
regulation of receptor recycling	IEA
vesicle budding from membrane	IBA
autophagy	IMP	17984323
nucleus organization	IMP	20616062

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

catabolic process [inference]

cellular catabolic process [inference]

autophagy

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular process [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

multivesicular body sorting pathway

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

cell cycle process [inference]

cytokinetic process [inference]

mitotic cytokinetic process [inference]

midbody abscission

mitotic cell cycle process [inference]

mitotic metaphase chromosome alignment

mitotic cytokinetic process [inference]

midbody abscission

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

late endosome to lysosome transport

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

process utilizing autophagic mechanism [inference]

autophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization

vacuole organization [inference]

vacuole fusion [inference]

vesicle fusion with vacuole

vesicle organization [inference]

vesicle budding from membrane

vesicle fusion [inference]

endosome organization [inference]

multivesicular body organization [inference]

multivesicular body assembly

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

vacuole fusion [inference]

vesicle fusion with vacuole

organelle assembly [inference]

multivesicular body assembly

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

ESCRT complex disassembly [inference]

ESCRT III complex disassembly

cellular component assembly [inference]

organelle assembly [inference]

multivesicular body assembly

membrane assembly [inference]

nuclear membrane reassembly

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

ESCRT complex disassembly [inference]

ESCRT III complex disassembly

membrane organization [inference]

vesicle budding from membrane

plasma membrane organization [inference]

plasma membrane repair

membrane fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

midbody abscission

membrane assembly [inference]

nuclear membrane reassembly

nuclear membrane organization [inference]

nuclear membrane reassembly

membrane fission

lysosomal membrane organization [inference]

multivesicular body-lysosome fusion

viral process [inference]

viral release from host cell [inference]

non-lytic viral release [inference]

viral budding from plasma membrane

viral budding

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

exit from host cell [inference]

viral release from host cell [inference]

non-lytic viral release [inference]

viral budding from plasma membrane

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

response to peptide [inference]

response to muramyl dipeptide [inference]

cellular response to muramyl dipeptide

cellular response to peptide [inference]

cellular response to muramyl dipeptide

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to peptide [inference]

cellular response to muramyl dipeptide

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

response to peptide [inference]

response to muramyl dipeptide [inference]

cellular response to muramyl dipeptide

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to peptide [inference]

response to muramyl dipeptide [inference]

cellular response to muramyl dipeptide

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to peptide [inference]

cellular response to muramyl dipeptide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

multivesicular body sorting pathway

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

late endosome to lysosome transport

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

late endosome to lysosome transport

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

establishment of organelle localization [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

organelle localization [inference]

chromosome localization [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

establishment of organelle localization [inference]

establishment of chromosome localization [inference]

metaphase chromosome alignment [inference]

mitotic metaphase chromosome alignment

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

late endosome to lysosome transport

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of macromolecule metabolic process [inference]

regulation of receptor recycling

regulation of signaling [inference]

regulation of receptor recycling

regulation of cellular process [inference]

regulation of microtubule-based process [inference]

regulation of centrosome cycle [inference]

regulation of centrosome duplication

regulation of microtubule cytoskeleton organization [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization [inference]

regulation of mitotic spindle assembly

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of cellular component biogenesis [inference]

regulation of organelle assembly [inference]

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization [inference]

regulation of mitotic spindle assembly

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of organelle assembly [inference]

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of centrosome cycle [inference]

regulation of centrosome duplication

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of centrosome cycle [inference]

regulation of centrosome duplication

regulation of spindle organization [inference]

regulation of mitotic spindle organization [inference]

regulation of mitotic spindle assembly

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

Displaying entries **11 - 14** of 14 in total

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GO Term	Evidence Code	PMID
midbody	IDA	26040712
multivesicular body membrane	IDA	16554368
extracellular exosome	HDA	19056867 20458337 23533145
amphisome membrane	IDA	17984323

GO Hierarchy

cellular component

protein-containing complex [inference]

ESCRT complex [inference]

ESCRT III complex

membrane protein complex [inference]

ESCRT III complex

nuclear protein-containing complex [inference]

nuclear pore

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane [inference]

multivesicular body membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

autophagosome membrane

amphisome membrane

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

late endosome membrane [inference]

multivesicular body membrane

midbody

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

intracellular non-membrane-bounded organelle [inference]

kinetochore

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

supramolecular complex [inference]

kinetochore

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule [inference]

spindle microtubule [inference]

kinetochore microtubule

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	15644320 16730941 17711858 18385515 21543490 21988832 22484091 23105106 25416956 26496610 27812135 28514442 32296183 33961781
cadherin binding	HDA	25468996

GO Hierarchy

molecular function

binding [inference]

protein binding

cell adhesion molecule binding [inference]

cadherin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

charged multivesicular body protein

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
late endosome to vacuole transport via multivesicular body sorting pathway
vacuolar transport

Displaying 1 entry
InterPro
Snf7 family

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	26456	Xenbase:XB-GENE-856594
Xenopus tropicalis	36846	Xenbase:XB-GENE-856594
Xenopus tropicalis	51510	Xenbase:XB-GENE-856594
Xenopus tropicalis	57715	Xenbase:XB-GENE-856594
Mus musculus	76959		MOUSE42602
Xenopus tropicalis	173351	Xenbase:XB-GENE-856594
Xenopus tropicalis	246538	Xenbase:XB-GENE-856594
Rattus norvegicus	297995		RATNO32630
Canis lupus familiaris	474741		CANLF02242
Bos taurus	539781		BOVIN34809

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Acknowledgements