ectonucleotide pyrophosphatase/phosphodiesterase 1
| UniProt | Protein Name |
|---|---|
| P22413 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| generation of precursor metabolites and energy | ||
| phosphate-containing compound metabolic process | ||
| immune response | ||
| nucleoside triphosphate catabolic process | ||
| nucleoside triphosphate catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| lysosomal membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleic acid binding | ||
| 3',5'-cyclic-AMP phosphodiesterase activity | ||
| exonuclease activity | ||
| phosphodiesterase I activity | ||
| phosphodiesterase I activity |
| Gene Ontology |
|---|
| hydrolase activity |
| metal ion binding |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050644 | arterial calcification of infancy | |
| DOID:0060887 | ossification of the posterior longitudinal ligament of spine | |
| DOID:1287 | cardiovascular system disease | |
| DOID:783 | end stage renal disease | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
| HPO ID | HPO Term |
|---|---|
| HP:0000685 | Hypoplasia of teeth |
| HP:0000737 | Irritability |
| HP:0000765 | Abnormal thorax morphology |
| HP:0000821 | Hypothyroidism |
| HP:0000822 | Hypertension |
| HP:0000855 | Insulin resistance |
| HP:0000951 | Abnormality of the skin |
| HP:0000961 | Cyanosis |
| HP:0000962 | Hyperkeratosis |
| HP:0000969 | Edema |
| Disease ID | Disease Name |
|---|---|
| OMIM:208000 |
|
| OMIM:601665 |
|
| ORPHA:289176 |
|
| ORPHA:758 |
|
| OMIM:613312 |
|
| OMIM:615522 |
|
| OMIM:125853 |
|
| ORPHA:51608 |
|
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: April 6, 2026