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MIRAGE
ghrelin and obestatin prepropeptide
Summary
- Gene Symbol
-
- GHRL
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Amidation
- Direct protein sequencing
- Hormone
- Lipoprotein
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9UBU3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| gastric acid secretion | ||
| negative regulation of endothelial cell proliferation | ||
| glucose metabolic process | ||
| G protein-coupled receptor signaling pathway | ||
| G protein-coupled receptor signaling pathway |
GO Hierarchy
- negative regulation of locomotion
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of secretion [inference]
positive regulation of transport [inference]
regulation of protein transport [inference]
regulation of peptide transport [inference]
regulation of cellular localization [inference]
regulation of circadian rhythm [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of transport [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular localization [inference]
regulation of secretion by cell [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of system process [inference]
regulation of behavior [inference]
positive regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| endoplasmic reticulum lumen |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor binding | ||
| protein binding | ||
| growth hormone-releasing hormone activity | ||
| growth hormone-releasing hormone activity | ||
| growth hormone-releasing hormone activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- appetite-regulating hormone
- Functional Category
-
- G: Carbohydrate transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| InterPro |
|---|
| Motilin/ghrelin-associated peptide |
| Preproghrelin peptide |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11981 | morbid obesity | |
| DOID:4914 | esophagus adenocarcinoma | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9743 | diabetic neuropathy | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 51738 | ZFIN:ZDB-GENE-070622-2 | ||
| 58991 | MOUSE50237 | ||
| 59301 | RATNO29225 | ||
| 281192 | BOVIN18021 | ||
| 396728 | PIGXX04573 | ||
| 403587 | CANLF07282 | ||
| 493844 | FELCA03835 | ||
| 100058008 | HORSE10863 | ||
| 100303671 | MELGA03986 | ||
| 100452667 | PONAB27096 |
