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CD244 molecule

Summary

Gene Symbol

CD244

Organism

Homo sapiens (human)

External Links

NCBI Gene

51744

PubChem

51744

Alliance of Genome Resources

HGNC:18171

JoGo

CD244

TogoVar

CD244

Annotation

Keyword

Adaptive immunity
Alternative splicing
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Innate immunity
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9BZW8	NK cell activation-inducing ligand NK cell type I receptor protein 2B4 SLAM family member 4 Signaling lymphocytic activation molecule 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
adaptive immune response	IEA
natural killer cell activation involved in immune response	IDA	11714776
natural killer cell activation involved in immune response	IBA
immune response	IBA
signal transduction	TAS	10358138

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

natural killer cell activation involved in immune response

immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

natural killer cell activation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

natural killer cell activation involved in immune response

natural killer cell activation

natural killer cell activation involved in immune response

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

natural killer cell activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

natural killer cell activation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

natural killer cell activation involved in immune response

natural killer cell activation

natural killer cell activation involved in immune response

signal transduction

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

natural killer cell activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

natural killer cell activation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

natural killer cell activation involved in immune response

natural killer cell activation

natural killer cell activation involved in immune response

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of alcohol biosynthetic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of phosphate metabolic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of small molecule metabolic process [inference]

positive regulation of small molecule metabolic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of alcohol biosynthetic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of carbohydrate biosynthetic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

regulation of cellular process [inference]

signal transduction

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of phosphate metabolic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of granzyme B production

positive regulation of inositol phosphate biosynthetic process

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of granzyme B production [inference]

positive regulation of granzyme B production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
external side of plasma membrane	IDA	17213291
external side of plasma membrane	IBA
membrane raft	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

membrane microdomain [inference]

membrane raft

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11489943 15153464 15841490 16002700 16920955 16983070 18296487 20164429 23346089 24642916 26221972
signaling receptor activity	IDA	27249817
MHC class I protein binding	IDA	20164429
MHC class I protein binding	IBA