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cyclin dependent kinase 12
Summary
- Gene Symbol
-
- CDK12
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Chromosomal rearrangement
- Host-virus interaction
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- mRNA splicing
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of MAP kinase activity | ||
| positive regulation of transcription by RNA polymerase II | ||
| protein autophosphorylation | ||
| regulation of cell cycle | ||
| negative regulation of stem cell differentiation |
GO Hierarchy
- regulation of cell cycle
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cyclin K-CDK12 complex | ||
| nucleus | ||
| nucleoplasm | ||
| nucleoplasm | ||
| cyclin/CDK positive transcription elongation factor complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase activity | ||
| cyclin-dependent protein serine/threonine kinase activity | ||
| protein binding | ||
| ATP binding | ||
| RNA polymerase II CTD heptapeptide repeat kinase activity |
GO Hierarchy
- cyclin-dependent protein serine/threonine kinase activity
- RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
- RNA polymerase II CTD heptapeptide repeat S2 kinase activity
- RNA polymerase II CTD heptapeptide repeat T4 kinase activity
- RNA polymerase II CTD heptapeptide repeat S5 kinase activity
- RNA polymerase II CTD heptapeptide repeat S7 kinase activity
- protein serine kinase activity
- cyclin-dependent protein serine/threonine kinase activity
- RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
- RNA polymerase II CTD heptapeptide repeat S2 kinase activity
- RNA polymerase II CTD heptapeptide repeat T4 kinase activity
- RNA polymerase II CTD heptapeptide repeat S5 kinase activity
- RNA polymerase II CTD heptapeptide repeat S7 kinase activity
- protein serine kinase activity
- cyclin-dependent protein serine/threonine kinase activity
- RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
- RNA polymerase II CTD heptapeptide repeat S2 kinase activity
- RNA polymerase II CTD heptapeptide repeat T4 kinase activity
- RNA polymerase II CTD heptapeptide repeat S5 kinase activity
- RNA polymerase II CTD heptapeptide repeat S7 kinase activity
- protein serine kinase activity
- RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
- RNA polymerase II CTD heptapeptide repeat S2 kinase activity
- RNA polymerase II CTD heptapeptide repeat T4 kinase activity
- RNA polymerase II CTD heptapeptide repeat S5 kinase activity
- RNA polymerase II CTD heptapeptide repeat S7 kinase activity
