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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
acyl-CoA oxidase 1
Summary
- Gene Symbol
-
- ACOX1
- Aliases
-
- PALMCOX
- palmitoyl-CoA oxidase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Deafness
- Disease variant
- FAD
- Fatty acid metabolism
- Neuropathy
- Oxidoreductase
- Peroxisome
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q15067 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| hydrogen peroxide biosynthetic process | ||
| fatty acid beta-oxidation using acyl-CoA oxidase | ||
| spermatogenesis | ||
| fatty acid catabolic process | ||
| lipid metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
catabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol |
|
|
| membrane | ||
| peroxisome | ||
| peroxisomal membrane | ||
| peroxisomal matrix |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| flavin adenine dinucleotide binding | ||
| protein homodimerization activity | ||
| fatty acid binding | ||
| acyl-CoA oxidase activity | ||
| PDZ domain binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:162 | cancer | |
| DOID:1826 | epilepsy | |
| DOID:2340 | craniosynostosis | |
| DOID:2848 | obsolete melancholia | |
| DOID:3234 | central nervous system lymphoma | |
| DOID:3526 | cerebral infarction | |
| DOID:3571 | liver cancer | |
| DOID:4964 | neurotic disorder | |
| DOID:539 | ophthalmoplegia | |
| DOID:540 | strabismus |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0002355 | Difficulty walking |
| HP:0002376 | Developmental regression |
| HP:0002415 | Leukodystrophy |
| HP:0002500 | Abnormal cerebral white matter morphology |
| HP:0002522 | Areflexia of lower limbs |
| HP:0002747 | Respiratory insufficiency due to muscle weakness |
| HP:0002910 | Elevated circulating hepatic transaminase concentration |
| HP:0003186 | Inverted nipples |
| HP:0003390 | Sensory axonal neuropathy |
| HP:0003487 | Babinski sign |
| Disease ID | Disease Name |
|---|---|
| ORPHA:2971 |
|
| OMIM:264470 |
|
| OMIM:618960 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002411
- Gene Name
- acyl-CoA oxidase 1, palmitoyl
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100083493 | ORNAN00181 | ||
| 100401745 | CALJA36203 | ||
| 105577707 | CERAT23023 | ||
| 705197 | MACMU14462 | ||
| 105469186 | MACNE15237 | ||
| 101014975 | PAPAN15053 | ||
| 105540940 | MANLE00179 | ||
| 101145668 | GORGO33454 | ||
| 100984758 | PANPA17972 | ||
| 454895 | PANTR15466 |
