ATPase H+ transporting V1 subunit A
| UniProt | Protein Name |
|---|---|
| P38606 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular iron ion homeostasis | ||
| vacuolar acidification | ||
| lysosomal lumen acidification | ||
| lysosomal lumen acidification | ||
| proton motive force-driven ATP synthesis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| vacuolar proton-transporting V-type ATPase, V1 domain | ||
| nucleoplasm | ||
| lysosomal membrane | ||
| lysosomal membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| ATP binding | ||
| ATP hydrolysis activity | ||
| proton-transporting ATP synthase activity, rotational mechanism | ||
| proton-transporting ATPase activity, rotational mechanism |
| Gene Ontology |
|---|
| GTP binding |
| nucleotide binding |
| InterPro |
|---|
| Dynamin |
| P-loop containing nucleoside triphosphate hydrolase |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070129 | autosomal recessive cutis laxa type IID | |
| DOID:0112275 | developmental and epileptic encephalopathy 93 |
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000023 | Inguinal hernia |
| HP:0000054 | Micropenis |
| HP:0000218 | High palate |
| HP:0000252 | Microcephaly |
| HP:0000253 | Progressive microcephaly |
| HP:0000272 | Malar flattening |
| HP:0000278 | Retrognathia |
| HP:0000298 | Mask-like facies |
| Disease ID | Disease Name |
|---|---|
| OMIM:618012 |
|
| ORPHA:357074 |
|
| ORPHA:442835 |
|
| OMIM:617403 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 523 | Xenbase:XB-GENE-990439 | ||
| 11964 | Xenbase:XB-GENE-990439 | MOUSE17684 | |
| 37950 | Xenbase:XB-GENE-990439 | ||
| 84620 | Xenbase:XB-GENE-990439 | ||
| 240119 | Xenbase:XB-GENE-990439 | ||
| 282147 | BOVIN14516 | ||
| 301155 | Xenbase:XB-GENE-990439 | ||
| 337583 | DANRE51290 | ||
| 394110 | DANRE36501 | ||
| 403116 | Xenbase:XB-GENE-990439 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: December 8, 2025