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Guidelines

MIRAGE

vacuolar protein sorting 37A

Summary

Gene Symbol

Vps37a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

52348

PubChem

52348

Alliance of Genome Resources

MGI:1261835

Annotation

Keyword

Alternative splicing
Coiled coil
Endosome
Membrane
Nucleus
Phosphoprotein
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3UV99
Q8CHS8	ESCRT-I complex subunit VPS37A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
protein targeting to membrane	IBA
protein targeting to vacuole	IBA
protein transport	IEA
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ISS
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein targeting [inference]

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization to membrane [inference]

protein targeting to membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
ESCRT I complex	ISS
ESCRT I complex	ISO
ESCRT I complex	IBA
nucleoplasm	ISO
nucleoplasm	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

ESCRT complex [inference]

ESCRT I complex

membrane protein complex [inference]

ESCRT I complex

cellular anatomical entity [inference]

nucleoplasm

microtubule organizing center [inference]

centrosome

cytosol

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

late endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying 1 entry
GO Term	Evidence Code	PMID
molecular_function	ND

GO Hierarchy

molecular function

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Vacuolar protein sorting-associated protein

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
protein targeting to membrane
protein targeting to vacuole
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Displaying **all 4** entries
InterPro
ESCRT assembly domain
Helix hairpin bin domain superfamily
Modifier of rudimentary, Modr
Ubiquitin-conjugating enzyme/RWD-like

Ortholog

Displaying entry **71 - 71** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Ursus americanus	123780434		URSAM21714

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: December 8, 2025