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leucine rich repeat containing 8 VRAC subunit C

Summary

Gene Symbol

LRRC8C

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 527708
PubChem: 527708

Annotation

Keyword

Cell membrane
Endoplasmic reticulum
Glycoprotein
Ion channel
Leucine-rich repeat
Phosphoprotein
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A5PK13	Leucine-rich repeat-containing protein 8C

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
fat cell differentiation
protein hexamerization
monoatomic anion transmembrane transport
aspartate transmembrane transport
cyclic-GMP-AMP transmembrane import across plasma membrane

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

purine-containing compound transmembrane transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

import across plasma membrane [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein hexamerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein hexamerization

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

purine-containing compound transmembrane transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

import across plasma membrane [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport

amino acid transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

cyclic-GMP-AMP transmembrane import across plasma membrane

organophosphate ester transport [inference]

nucleotide transport [inference]

purine nucleotide transport [inference]

guanine nucleotide transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

purine ribonucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

adenine nucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

cyclic nucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport

amino acid transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

purine nucleotide transport [inference]

guanine nucleotide transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

purine ribonucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

adenine nucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

cyclic nucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

purine-containing compound transmembrane transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

carbohydrate derivative transport [inference]

purine ribonucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

purine nucleotide transport [inference]

guanine nucleotide transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

purine ribonucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

adenine nucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

cyclic nucleotide transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

nucleotide transmembrane transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

purine-containing compound transmembrane transport [inference]

guanine nucleotide transmembrane transport [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

import into cell [inference]

cyclic-GMP-AMP transmembrane import across plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm
plasma membrane
endoplasmic reticulum membrane
monoatomic ion channel complex

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IEA	22301074
volume-sensitive anion channel activity

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

volume-sensitive anion channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

volume-sensitive anion channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

volume-sensitive anion channel activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **1 - 10** of **108** in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	84230	HUMAN50698
Mus musculus	100604	MOUSE43630
Rattus norvegicus	289443	RATNO08404
Pan troglodytes	457009	PANTR21548
Canis lupus familiaris	490168	CANLF16927
Danio rerio	571216	DANRE38531
Macaca mulatta	696086	MACMU23298
Equus caballus	100051898	HORSE34336
Equus caballus	100061419	HORSE34336
Ornithorhynchus anatinus	100091534	ORNAN19571