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pannexin 1

Summary

Gene Symbol

PANX1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 528169
PubChem: 528169

Annotation

Keyword

Glycoprotein
Ion channel
Reference proteome
S-nitrosylation
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
D7R519

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
positive regulation of interleukin-1 beta production
monoatomic cation transport	IEA	30032202
positive regulation of interleukin-1 production	IEA	30032202
cell-cell signaling

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

signaling [inference]

cell-cell signaling

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane
gap junction
bleb
endoplasmic reticulum

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

gap junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

bleb

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
leak channel activity
channel activity	IEA	30032202
signaling receptor binding
ATP transmembrane transporter activity
calcium channel activity

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

ATP transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

organophosphate ester transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

purine nucleotide transmembrane transporter activity [inference]

adenine nucleotide transmembrane transporter activity [inference]

ATP transmembrane transporter activity

purine ribonucleotide transmembrane transporter activity [inference]

ATP transmembrane transporter activity

nucleobase-containing compound transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

purine nucleotide transmembrane transporter activity [inference]

adenine nucleotide transmembrane transporter activity [inference]

ATP transmembrane transporter activity

purine ribonucleotide transmembrane transporter activity [inference]

ATP transmembrane transporter activity

passive transmembrane transporter activity [inference]

channel activity

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

wide pore channel activity

narrow pore channel activity [inference]

leak channel activity

carbohydrate derivative transmembrane transporter activity [inference]

purine ribonucleotide transmembrane transporter activity [inference]

ATP transmembrane transporter activity

salt transmembrane transporter activity [inference]

ATP transmembrane transporter activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

binding [inference]

protein binding [inference]

signaling receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Innexin

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
monoatomic ion transport

Displaying 1 entry
InterPro
Innexin

Ortholog

Displaying entries **81 - 90** of **119** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Hippocampus comes	109527239		HIPCM04283
Bos indicus	109554443	9915_0:0048bb
Seriola dumerili	111229371		SERDU17946
Amphiprion ocellaris	111581300		AMPOC19511
Oryzias melastigma	112137629		ORYME29101
Vulpes vulpes	112915763		VULVU08025
Astatotilapia calliptera	113023720		ASTCA33896
Anabas testudineus	113162687		ANATE16156
Electrophorus electricus	113587318		ELEEL39471
Electrophorus electricus	113591635		ELEEL46764

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements