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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Summary
- Gene Symbol
-
- PIK3CG
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Angiogenesis
- Cell membrane
- Chemotaxis
- Cytoplasm
- Disease variant
- Endocytosis
- Immunity
- Inflammatory response
- Kinase
- Lipid metabolism
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of fibroblast apoptotic process |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase activity | ||
| ephrin receptor binding | ||
| 1-phosphatidylinositol-3-kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine kinase activity |
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060708 | lymphoproliferative syndrome 2 | |
| DOID:0060764 | autosomal recessive Robinow syndrome | |
| DOID:0060765 | autosomal dominant Robinow syndrome 2 | |
| DOID:0060766 | autosomal dominant Robinow syndrome 1 | |
| DOID:0060767 | autosomal dominant Robinow syndrome 3 | |
| DOID:0060782 | EEC syndrome | |
| DOID:0060783 | ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3 | |
| DOID:0060784 | ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 1 | |
| DOID:0060802 | syndromic X-linked intellectual disability Snyder type | |
| DOID:0060891 | Parkinson's disease 19A |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0005425 | Recurrent sinopulmonary infections |
| HP:0011945 | Bronchiolitis obliterans organizing pneumonia |
| HP:0012156 | Hemophagocytosis |
| HP:0012312 | Monocytopenia |
| HP:0012378 | Fatigue |
| HP:0100721 | Mediastinal lymphadenopathy |
| Disease ID | Disease Name |
|---|---|
| OMIM:619802 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP000468
- Gene Name
- phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 174762 | WB:WBGene00000090 | ||
| 100180112 | CIOIN10552 | ||
| 103175665 | CALMI07698 | ||
| 102353565 | LATCH06525 | ||
| 406598 | ZFIN:ZDB-GENE-040426-2532 | DANRE34488 | |
| 103041836 | ASTMX20676 | ||
| 108279798 | ICTPU12268 | ||
| 113575802 | ELEEL16633 | ||
| 106576084 | SALSA52429 | ||
| 106609208 | SALSA135073 |
