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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Summary
- Gene Symbol
-
- PIK3CG
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Angiogenesis
- Cell membrane
- Chemotaxis
- Cytoplasm
- Disease variant
- Endocytosis
- Immunity
- Inflammatory response
- Kinase
- Lipid metabolism
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of MAP kinase activity | ||
| adaptive immune response |
|
|
| sphingosine-1-phosphate receptor signaling pathway | ||
| G protein-coupled receptor signaling pathway | ||
| cell migration |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| 1-phosphatidylinositol-4-phosphate 3-kinase activity | ||
| 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity | ||
| ATP binding | ||
| protein binding | ||
| protein kinase activity |
|
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:6612 | leukocyte adhesion deficiency | |
| DOID:6683 | X-linked Aarskog syndrome | |
| DOID:6688 | autoimmune lymphoproliferative syndrome | |
| DOID:6713 | cerebrovascular disease | |
| DOID:6726 | fibrillary astrocytoma | |
| DOID:6811 | juvenile pilocytic astrocytoma | |
| DOID:6812 | childhood pilocytic astrocytoma | |
| DOID:8632 | Kaposi's sarcoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:686 | liver carcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000010 | Recurrent urinary tract infections |
| HP:0000403 | Recurrent otitis media |
| HP:0000964 | Eczematoid dermatitis |
| HP:0001252 | Hypotonia |
| HP:0001433 | Hepatosplenomegaly |
| HP:0001581 | Recurrent skin infections |
| HP:0001742 | Nasal congestion |
| HP:0001744 | Splenomegaly |
| HP:0001873 | Thrombocytopenia |
| Disease ID | Disease Name |
|---|---|
| OMIM:619802 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP000468
- Gene Name
- phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115036690 | ECHNA41811 | ||
| 115403926 | SALFA10000 | ||
| 113490925 | ATHCN05581 | ||
| 105815179 | PROCO05914 | ||
| 109060929 | CYPCA63285 | ||
| 109064199 | CYPCA33330 | ||
| 103732179 | NANGA02072 | ||
| 116442892 | CORMO19998 | ||
| 103252973 | CARSF17749 | ||
| 115605592 | STRHB21515 |
