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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
polycystin 2, transient receptor potential cation channel
Summary
- Gene Symbol
-
- PKD2
- Organism
- Bos taurus (domestic cattle)
External Links
- NCBI Gene
- 530393
- KEGG Gene ID
- bta:530393
- PubChem
- 530393
Annotation
- Keyword
-
- Calcium channel
- Cell membrane
- Cell projection
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Metal-binding
- Methylation
- Phosphoprotein
- Potassium channel
- Reference proteome
- Secreted
- Transmembrane helix
- Voltage-gated channel
- Wnt signaling pathway
- Proteins
| UniProt | Protein Name |
|---|---|
| Q4GZT3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| potassium ion transmembrane transport | ||
| release of sequestered calcium ion into cytosol | ||
| Wnt signaling pathway |
|
|
| protein tetramerization |
|
|
| protein heterotetramerization |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane |
|
|
| endoplasmic reticulum |
|
|
| ciliary membrane |
|
|
| basolateral plasma membrane |
|
|
| polycystin complex |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| voltage-gated sodium channel activity | ||
| calcium channel activity |
|
|
| muscle alpha-actinin binding | ||
| voltage-gated calcium channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Polycystic kidney disease
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium channel activity |
| calcium ion binding |
| detection of mechanical stimulus |
| InterPro |
|---|
| Polycystic kidney disease type 2 protein |
| Polycystin cation channel, PKD1/PKD2 |
| Polycystin domain |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 125137345 | 41426_0:003950 | |||
| 128049752 | 37181_0:001998 | |||
| 129561581 | 68408_0:003438 | |||
| 129657676 | 346063_0:002869 | |||
| 130849153 | 575201_0:0010f8 |
