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translocase of outer mitochondrial membrane 40

Summary

Gene Symbol

Tomm40

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

53333

PubChem

53333

Alliance of Genome Resources

MGI:1858259

Annotation

Keyword

Direct protein sequencing
Mitochondrion outer membrane
Porin
Protein transport
Reference proteome
Transmembrane beta strand

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9QYA2	Mitochondrial outer membrane protein of 35 kDa Protein Haymaker Translocase of outer membrane 40 kDa subunit homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein targeting to mitochondrion	ISS
protein targeting to mitochondrion	ISO
monoatomic ion transport	IEA
ion transport	IEA
protein import into mitochondrial matrix	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

protein transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

transmembrane transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

mitochondrial transmembrane transport [inference]

protein import into mitochondrial matrix

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrial membrane organization [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

membrane organization [inference]

mitochondrial membrane organization [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

protein transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of localization [inference]

transport [inference]

monoatomic ion transport

mitochondrial transport [inference]

mitochondrial transmembrane transport [inference]

protein import into mitochondrial matrix

transmembrane transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

mitochondrial transmembrane transport [inference]

protein import into mitochondrial matrix

organic substance transport [inference]

protein transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

nitrogen compound transport [inference]

protein transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

protein transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of localization in cell [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to mitochondrion

protein transport [inference]

protein transmembrane transport [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to organelle [inference]

protein transmembrane import into intracellular organelle [inference]

protein import into mitochondrial matrix

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein insertion into membrane [inference]

protein insertion into mitochondrial membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial membrane

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	IDA	12931191
mitochondrion	HDA	14651853 18614015
mitochondrial outer membrane	ISO
mitochondrial outer membrane	IDA	28376086

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

pore complex

outer mitochondrial membrane protein complex [inference]

mitochondrial outer membrane translocase complex

mitochondrial protein-containing complex [inference]

outer mitochondrial membrane protein complex [inference]

mitochondrial outer membrane translocase complex

cellular anatomical entity [inference]

cytosol

membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

organelle membrane contact site [inference]

mitochondria-associated endoplasmic reticulum membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
monoatomic cation channel activity	ISO
protein transmembrane transporter activity	ISO
protein transmembrane transporter activity	IBA
protein transmembrane transporter activity	IEA
porin activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

wide pore channel activity [inference]

porin activity

macromolecule transmembrane transporter activity [inference]

protein transmembrane transporter activity

protein transporter activity [inference]

protein transmembrane transporter activity

binding [inference]

protein binding [inference]

preprotein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

mitochondrial import receptor subunit

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
protein import into mitochondrial matrix

Displaying **all 3** entries
InterPro
Eukaryotic porin/Tom40
Porin domain superfamily
Tom40

Ortholog

Displaying entries **1 - 10** of 79 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	10452	Xenbase:XB-GENE-995150	HUMAN44277
Xenopus tropicalis	53333	Xenbase:XB-GENE-995150
Rattus norvegicus	308416		RATNO16339
Danio rerio	322645		DANRE11210
Danio rerio	405895		DANRE16317
Bos taurus	510219		BOVIN11279
Canis lupus familiaris	611055		CANLF00953
Macaca mulatta	713297		MACMU18986
Equus caballus	100146715		HORSE02236
Ciona intestinalis	100178867		CIOIN07160