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nucleoporin 54

Summary

Gene Symbol

NUP54

Organism

Homo sapiens (human)

External Links

NCBI Gene

53371

PubChem

53371

Alliance of Genome Resources

HGNC:17359

Annotation

Keyword

3D-structure
Alternative splicing
Dystonia
Glycoprotein
Membrane
Nuclear pore complex
Reference proteome
Repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7Z3B4	54 kDa nucleoporin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
NLS-bearing protein import into nucleus	IBA
nuclear pore organization	IBA
mRNA transport	IEA
protein localization to nuclear inner membrane	IBA
nucleocytoplasmic transport	NAS	27016207

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to nuclear inner membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

protein localization to nuclear envelope [inference]

protein localization to nuclear inner membrane

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

protein localization to membrane [inference]

protein localization to nuclear inner membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nuclear pore organization

protein-containing complex organization [inference]

nuclear pore organization

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

protein localization to nuclear envelope [inference]

protein localization to nuclear inner membrane

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

protein localization to membrane [inference]

protein localization to nuclear inner membrane

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

mRNA transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to nuclear inner membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

protein localization to nuclear envelope [inference]

protein localization to nuclear inner membrane

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

protein localization to membrane [inference]

protein localization to nuclear inner membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of protein localization to nucleus [inference]

regulation of protein import into nucleus

regulation of cellular process [inference]

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of protein localization to nucleus [inference]

regulation of protein import into nucleus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nuclear membrane	IEA
nuclear pore central transport channel	IBA
nuclear pore	NAS	24315095
nuclear envelope	IDA TAS	24315095

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

nuclear membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	16189514 21516116 21994455 25416956 26496610 27194810 30021884 31413325 31515488 32296183 32353859 32814053 33060197 33961781 35271311 36217030
protein-containing complex binding	IEA
structural constituent of nuclear pore	IBA
identical protein binding	IEA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

protein binding

identical protein binding

protein-containing complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

nucleoporin

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
NLS-bearing protein import into nucleus
nuclear pore organization
protein localization to nuclear inner membrane

Displaying **all 2** entries
InterPro
Nucleoporin Nup54, alpha-helical domain
Nucleoporin Nup54/Nup57/Nup44

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060956	dystonia 37, early-onset with striatal lesions	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 98 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	36360		FB:FBgn0033737
Rattus norvegicus	53372		RGD:619926	RATNO08573
Caenorhabditis elegans	177836		WB:WBGene00003787
Mus musculus	269113		MGI:1920460	MOUSE45782
Danio rerio	335750		ZFIN:ZDB-GENE-040426-2263
Xenopus laevis	398799		Xenbase:XB-GENE-948042
Pan troglodytes	461240	9598_0:0014bb		PANTR33698
Bos taurus	506916			BOVIN31703
Xenopus tropicalis	550103		Xenbase:XB-GENE-948035
Macaca mulatta	700112			MACMU37663