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Guidelines

MIRAGE

cytochrome P450 family 2 subfamily U member 1

Summary

Gene Symbol

CYP2U1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 535227
KEGG Gene ID: bta:535227
PubChem: 535227

Annotation

Keyword

Heme
Lipid metabolism
Microsome
Mitochondrion inner membrane
Monooxygenase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q0IIF9	Long-chain fatty acid omega-monooxygenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
organic acid metabolic process	IEA	30032202
xenobiotic metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

small molecule metabolic process [inference]

organic acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process

cellular process [inference]

cellular metabolic process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202
intracellular membrane-bounded organelle	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying **all 4** entries
GO Term	Evidence Code	PMID
iron ion binding	IEA	22301074
steroid hydroxylase activity	IEA	30032202
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA	22301074 30032202
heme binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cytochrome P450

Functional Category

C: Energy production and conversion
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
heme binding
iron ion binding
metal ion binding
monooxygenase activity
organic acid metabolic process
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity

Displaying **all 4** entries
InterPro
Cytochrome P450 superfamily
Cytochrome P450, E-class, group I
Cytochrome P450, conserved site
Cytochrome P450

KEGG BRITE Database

Orthology

K07422

Name

long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]

References

14660610

Rhea

O₂ + hexadecanoate

H₂O + H⁺ + 16-hydroxyhexadecanoate

Enzyme

1.14.14.80

PMID

O₂ + (9Z)-octadecenoate

H₂O + H⁺ + 18-hydroxy-(9Z)-octadecenoate

Enzyme

1.14.14.80

PMID

an ω-methyl-long-chain fatty acid + O₂

an ω-hydroxy-long-chain fatty acid + H₂O + H⁺

Enzyme

1.14.14.80

PMID

O₂ + octadecanoate

H₂O + H⁺ + 18-hydroxyoctadecanoate

Enzyme

1.14.14.80

PMID

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026